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PMID: 8794097 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S. Review

Synaptic transmission at vertebrate hair cells.

Current opinion in neurobiology ·Vol. 6 ·No. 4 ·1996-08-00 ·Pages 514-9

Fuchs PA

Abstract

Mechanosensory hair cells release chemical transmitters onto associated afferent dendrites and respond to transmitters released by efferent neurons. Dihydropyridine-sensitive, voltage-gated calcium channels support transmitter release from hair cells and may be expressed preferentially at release sites. Recently, a novel subunit of the nicotinic acetylcholine receptor family, alpha9, was identified and found to be expressed in rat hair cells. It appears to mediate efferent inhibition via associated calcium-activated potassium channels.

MeSH Terms
Afferent Pathways/physiology Animals Calcium Channels/physiology Efferent Pathways/physiology Hair Cells, Auditory/physiology Ion Channel Gating Potassium Channels/physiology Receptors, Cholinergic/physiology Synaptic Transmission Vertebrates/physiology
Chemicals
Calcium Channels Potassium Channels Receptors, Cholinergic
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Fuchs P A
Hearing Science Center, 521 Traylor Building, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Baltimore, Maryland 21205, USA. [email protected]
Article Info
Journal
Current opinion in neurobiology
Abbr.
Curr Opin Neurobiol
ISSN
0959-4388
Published
1996-08-00
Pages
514-9
Language
English
Region
England
NLM ID
9111376
Subset
IM
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