Home LiteratureArticle Details

PMID: 8805328 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Review

Versatile molecular glue. Transcriptional control.

Current biology : CB ·Vol. 6 ·No. 8 ·1996-08-01 ·Pages 951-4

Janknecht R, Hunter T

Abstract

CBP and p300 are versatile coactivators that physically connect many DNA-binding factors to the basal transcription machinery. Phosphorylation by cyclin-dependent or signal-induced protein kinases may regulate their function.

MeSH Terms

Acetyltransferases Animals CREB-Binding Protein Cell Cycle Proteins/metabolism Cyclic AMP/metabolism Histone Acetyltransferases Nuclear Proteins/metabolism Phosphorylation Protein Kinases/metabolism Trans-Activators Transcription Factors/metabolism Transcription, Genetic p300-CBP Transcription Factors

Chemicals

Cell Cycle Proteins Nuclear Proteins Trans-Activators Transcription Factors Cyclic AMP Acetyltransferases CREB-Binding Protein Histone Acetyltransferases p300-CBP Transcription Factors p300-CBP-associated factor Protein Kinases

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Janknecht R

The Salk Institute Molecular Biology and Virology Laboratory, 10010 North Torrey Pines Road, La Jolla, California 92037, USA.

Hunter T

Article Info

Journal

Current biology : CB

Abbr.

Curr Biol

ISSN

0960-9822

DOI

10.1016/s0960-9822(02)00636-x

Published

1996-08-01

Pages

951-4

Language

English

Region

England

NLM ID

9107782

Subset

External Links

PubMed source DOI: 10.1016/s0960-9822(02)00636-x View journal details

Analysis Services

Versatile molecular glue. Transcriptional control.

Contact

WeChat Official Account