Nucleolar organizing regions of human chromosomes.

Human genetics ·Vol. 48 ·No. 2 ·1979-04-27 ·Pages 201-10

Ray M, Pearson J

Abstract

Silver-stained cells from 49 parents with a history of several abortions were compared with cells from 35 parents with normal liveborn children. The modal and mean number of silver-stained NORs (Ag-NORs) observed on D- or G-group chromosomes was similar in both groups and between males and females. Ag-NORs were randomly distributed on all five acrocentric pairs. The distribution and size of Ag-NORs within an individual was not random and was fairly consistent from cell to cell. The mean number of associations per cell was similar in both males and females of the abortion group and was less than the number of associations in controls. The probability of D- or G-group chromosomes being associated was near the expected probability of 0.6 for D-association and 0.4 for G-association. The frequency of association of any chromosome combination did not differ statistically from the expected values, though the number of associations, 15/22, was higher than expected.

MeSH Terms

Abortion, Spontaneous/genetics Adult Cell Nucleolus/ultrastructure Chromosomes, Human, 13-15/ultrastructure Chromosomes, Human, 21-22 and Y/ultrastructure Female Humans Male Pregnancy Probability Silver Staining and Labeling

Chemicals

Silver

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Ray M

Pearson J

References (25)

25 references, click to expand

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Article Info

Journal

Human genetics

Abbr.

Hum Genet

ISSN

0340-6717

DOI

10.1007/BF00286905

Published

1979-04-27

Pages

201-10

Language

English

Region

Germany

NLM ID

7613873

Subset

External Links

PubMed source DOI: 10.1007/BF00286905 View journal details

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Nucleolar organizing regions of human chromosomes.

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