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PMID: 8852849 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Differences in crossover frequency and distribution among three sibling species of Drosophila.

Genetics ·Vol. 142 ·No. 2 ·1996-02-00 ·Pages 507-23

True JR, Mercer JM, Laurie CC

Abstract

Comparisons of the genetic and cytogenetic maps of three sibling species of Drosophila reveal marked differences in the frequency and cumulative distribution of crossovers during meiosis. The maps for two of these species, Drosophila melanogaster and D. simulans, have previously been described, while this report presents new map data for D. mauritiana, obtained using a set of P element markers. A genetic map covering nearly the entire genome was constructed by estimating the recombination fraction for each pair of adjacent inserts. The P-based genetic map of mauritiana is approximately 1.8 times longer than the standard melanogaster map. It appears that mauritiana has higher recombination along the entire length of each chromosome, but the difference is greates in centromere-proximal regions of the autosomes. The mauritiana autosomes show little or no centromeric recombinational suppression, a characteristic that is prominent in melanogaster. D. simulans appears to be intermediate both in terms of total map length and intensity of the autosomal centromeric effect. These interspecific differences in recombination have important evolutionary implications for DNA sequence organization and variability. In particular, mauritiana is expected to differ from melanogaster in patterns and amounts of sequence variation and transposon insertions.

MeSH Terms
Animals Chromosome Mapping Crossing Over, Genetic Drosophila/genetics Drosophila melanogaster/genetics Eye Color/genetics Female Gene Frequency Male Recombination, Genetic
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
True J R
Department of Zoology, Duke University, Durham, North Carolina 27708, USA.
Mercer J M
Laurie C C
References (62)
62 references, click to expand
  1. Functional aspects of satellite DNA and heterochromatin.
    Int Rev Cytol. 1979;58:1-114 PMID: 391760
  2. Length and sequence variation in evening bat D-loop mtDNA.
    Genetics. 1991 Jul;128(3):607-17 PMID: 1874418
  3. Use of P-element-mediated transformation to identify the molecular basis of naturally occurring variants affecting Adh expression in Drosophila melanogaster.
    Genetics. 1987 Jan;115(1):129-40 PMID: 2881843
  4. The hitch-hiking effect of a favourable gene.
    Genet Res. 1974 Feb;23(1):23-35 PMID: 4407212
  5. The distribution of transposable elements within and between chromosomes in a population of Drosophila melanogaster. I. Element frequencies and distribution.
    Genet Res. 1992 Oct;60(2):103-14 PMID: 1334899
  6. The genetic control of meiosis.
    Annu Rev Genet. 1976;10:53-134 PMID: 797314
  7. Mismatch recognition in chromosomal interactions and speciation.
    Chromosoma. 1993 Jun;102(6):369-73 PMID: 8365347
  8. Analysis of P transposable element functions in Drosophila.
    Cell. 1984 Aug;38(1):135-46 PMID: 6088058
  9. Sequence of tRNA(Thr) and tRNA(Pro) from white sturgeon (Acipenser transmontanus) mitochondria.
    Nucleic Acids Res. 1988 Dec 23;16(24):11825 PMID: 3211756
  10. Chiasma interference as a function of genetic distance.
    Genetics. 1993 Mar;133(3):681-91 PMID: 8454209
  11. An inferred chiasma map of Drosophila melanogaster.
    Heredity (Edinb). 1976 Dec;37(3):405-11 PMID: 827535
  12. Simultaneous editing of multiple nucleic acid and protein sequences with ESEE.
    Comput Appl Biosci. 1989 Jul;5(3):233-4 PMID: 2766009
  13. Levels of naturally occurring DNA polymorphism correlate with recombination rates in D. melanogaster.
    Nature. 1992 Apr 9;356(6369):519-20 PMID: 1560824
  14. Chromosome segregation mechanisms.
    Genetics. 1974 Sep;78(1):205-13 PMID: 4442702
  15. The Theory of Multiple-Strand Crossing over.
    Genetics. 1936 May;21(3):155-99 PMID: 17246790
  16. Maximum likelihood estimation of the number of nucleotide substitutions from restriction sites data.
    Genetics. 1983 Sep;105(1):207-17 PMID: 6311668
  17. Mitochondrial DNA transmission genetics in crickets.
    Genetics. 1986 Nov;114(3):955-70 PMID: 3792825
  18. Genetic analysis of sex chromosomal meiotic mutants in Drosophilia melanogaster.
    Genetics. 1972 Jun;71(2):255-86 PMID: 4625747
  19. Heteroplasmy of short tandem repeats in mitochondrial DNA of Atlantic cod, Gadus morhua.
    Genetics. 1992 Sep;132(1):211-20 PMID: 1356884
  20. Replacement of bovine mitochondrial DNA by a sequence variant within one generation.
    Genetics. 1991 Sep;129(1):247-55 PMID: 1682213
  21. Relationships within the melanogaster species subgroup of the genus Drosophila (Sophophora). II. Phylogenetic relationships between six species based upon polytene chromosome banding sequences.
    Proc R Soc Lond B Biol Sci. 1976 May 18;193(1112):275-94 PMID: 6967
  22. Comparative studies of allozyme loci in Drosophila simulans and Drosophila melanogaster. I. Three dipeptidase loci.
    Biochem Genet. 1981 Feb;19(1-2):75-85 PMID: 6784720
  23. Protein binding to a single termination-associated sequence in the mitochondrial DNA D-loop region.
    Mol Cell Biol. 1993 Apr;13(4):2162-71 PMID: 8455604
  24. The genetic analysis of meiosis in female Drosophila melanogaster.
    Philos Trans R Soc Lond B Biol Sci. 1977 Mar 21;277(955):295-312 PMID: 16292
  25. Characterization of a meiotic control gene affecting recombination in Drosophila melanogaster.
    Hereditas. 1973;75(1):5-22 PMID: 4204896
  26. A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments.
    Gene. 1982 Oct;19(3):269-76 PMID: 6295880
  27. Variation in mitochondrial DNA and population structure of the Taipei treefrog Rhacophorus taipeianus in Taiwan.
    Mol Ecol. 1994 Jun;3(3):219-28 PMID: 8061878
  28. Mitochondrial DNA sequences in single hairs from a southern African population.
    Proc Natl Acad Sci U S A. 1989 Dec;86(23):9350-4 PMID: 2594772
  29. The effect of deleterious mutations on neutral molecular variation.
    Genetics. 1993 Aug;134(4):1289-303 PMID: 8375663
  30. Molecular population genetics of mtDNA size variation in crickets.
    Genetics. 1989 Mar;121(3):551-69 PMID: 2565855
  31. Genetic studies on heterochromatin in Drosophila melanogaster and their implications for the functions of satellite DNA.
    Chromosoma. 1978 Mar 22;66(1):71-98 PMID: 416935
  32. Mechanism of mitochondrial DNA replication in mouse L-cells: kinetics of synthesis and turnover of the initiation sequence.
    J Mol Biol. 1978 Feb 15;119(1):49-68 PMID: 633368
  33. The use of intensifying screens or organic scintillators for visualizing radioactive molecules resolved by gel electrophoresis.
    Methods Enzymol. 1980;65(1):363-71 PMID: 7374459
  34. Analysis of a genetic hitchhiking model, and its application to DNA polymorphism data from Drosophila melanogaster.
    Mol Biol Evol. 1993 Jul;10(4):842-54 PMID: 8355603
  35. Replication and transcription of vertebrate mitochondrial DNA.
    Annu Rev Cell Biol. 1991;7:453-78 PMID: 1809353
  36. Endotherms, ectotherms, and mitochondrial genome-size variation.
    J Mol Evol. 1993 Sep;37(3):281-95 PMID: 8230252
  37. Patterns of sequence variation in the mitochondrial D-loop region of shrews.
    Mol Biol Evol. 1994 Jan;11(1):9-21 PMID: 8121290
  38. Mitochondrial DNA length variation and heteroplasmy in populations of white sturgeon (Acipenser transmontanus).
    Genetics. 1992 Sep;132(1):221-8 PMID: 1398055
  39. Searching for pattern and mutation in the Drosophila genome with a P-lacZ vector.
    Genes Dev. 1989 Sep;3(9):1273-87 PMID: 2558049
  40. An analysis of regional constraints on exchange in Drosophila melanogaster using recombination-defective meiotic mutants.
    Genetics. 1984 Jan;106(1):45-71 PMID: 6420228
  41. Nucleotide sequence of the apocytochrome B gene in white sturgeon mitochondrial DNA.
    Nucleic Acids Res. 1989 Jun 12;17(11):4389 PMID: 2740232
  42. Body size, metabolic rate, generation time, and the molecular clock.
    Proc Natl Acad Sci U S A. 1993 May 1;90(9):4087-91 PMID: 8483925
  43. Meiotic segregation in Drosophila melanogaster females: molecules, mechanisms, and myths.
    Annu Rev Genet. 1993;27:281-317 PMID: 8122905
  44. Mitochondrial DNA polymorphism in a maternal lineage of Holstein cows.
    Proc Natl Acad Sci U S A. 1982 Aug;79(15):4686-90 PMID: 6289312
  45. EXCHANGE AND NONDISJUNCTION OF THE X CHROMOSOMES IN FEMALE DROSOPHILA MELANOGASTER.
    Genetics. 1964 Jan;49:109-22 PMID: 14105104
  46. Organelle gene diversity under migration, mutation, and drift: equilibrium expectations, approach to equilibrium, effects of heteroplasmic cells, and comparison to nuclear genes.
    Genetics. 1989 Mar;121(3):613-27 PMID: 2714640
  47. DIFFERENCE IN THE BEHAVIOR OF EU- AND HETERO-CHROMATIN: CROSSING-OVER.
    Nature. 1965 Feb 13;205:725-6 PMID: 14287435
  48. The evolutionary dynamics of repetitive DNA in eukaryotes.
    Nature. 1994 Sep 15;371(6494):215-20 PMID: 8078581
  49. A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequences.
    J Mol Evol. 1980 Dec;16(2):111-20 PMID: 7463489
  50. The effect of sequence homozygosity on the frequency of X-chromosomal exchange in Drosophila melanogaster females.
    Genetics. 1988 Nov;120(3):725-32 PMID: 3147211
  51. Extensive variation and heteroplasmy in size of mitochondrial DNA among geographic populations of Drosophila melanogaster.
    Proc Natl Acad Sci U S A. 1986 Nov;83(22):8813-7 PMID: 16578797
  52. The use of restriction endonucleases to measure mitochondrial DNA sequence relatedness in natural populations. III. Techniques and potential applications.
    J Mol Evol. 1981;17(4):214-26 PMID: 6267312
  53. Rates of mitochondrial DNA evolution in sharks are slow compared with mammals.
    Nature. 1992 May 14;357(6374):153-5 PMID: 1579163
  54. The Drosophila melanogaster dodecasatellite sequence is closely linked to the centromere and can form connections between sister chromatids during mitosis.
    J Cell Sci. 1993 May;105 ( Pt 1):41-50 PMID: 8360277
  55. The organization of genetic variation for recombination in Drosophila melanogaster.
    Genetics. 1986 Oct;114(2):525-47 PMID: 3095185
  56. Human mitochondrial DNA variation and evolution: analysis of nucleotide sequences from seven individuals.
    Genetics. 1983 Feb;103(2):287-312 PMID: 6299878
  57. Apparent absence of transposable elements related to the P elements of D. melanogaster in other species of Drosophila.
    Nature. 1984 Jul 26-Aug 1;310(5975):330-2 PMID: 6087152
  58. Length heteroplasmy of sturgeon mitochondrial DNA: an illegitimate elongation model.
    Genetics. 1990 Jan;124(1):157-63 PMID: 1968410
  59. Differing levels of dispersed repetitive DNA among closely related species of Drosophila.
    Proc Natl Acad Sci U S A. 1982 Aug;79(15):4570-4 PMID: 6956880
  60. Mitochondrial DNA evolution at a turtle's pace: evidence for low genetic variability and reduced microevolutionary rate in the Testudines.
    Mol Biol Evol. 1992 May;9(3):457-73 PMID: 1584014
  61. Population genetics and phylogenetics of DNA sequence variation at multiple loci within the Drosophila melanogaster species complex.
    Mol Biol Evol. 1993 Jul;10(4):804-22 PMID: 8355601
  62. Methods for computing the standard errors of branching points in an evolutionary tree and their application to molecular data from humans and apes.
    Mol Biol Evol. 1985 Jan;2(1):66-85 PMID: 2897060
Article Info
Journal
Genetics
Abbr.
Genetics
ISSN
0016-6731
DOI
10.1093/genetics/142.2.507
Published
1996-02-00
Pages
507-23
Language
English
Region
United States
NLM ID
0374636
PMCID
PMC1206984
Subset
IM
Grants
NIGMS NIH HHS · GM-47292 · United States
External Links
PubMed source DOI: 10.1093/genetics/142.2.507 PMC Full Text View journal details
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