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PMID: 887068 Published · ppublish English Journal Article

Mitochondrial genes in Podospora anserina: recombination and linkage.

Molecular & general genetics : MGG ·Vol. 153 ·No. 1 ·1977-05-20 ·Pages 11-21

Belcour L, Begel O

Abstract

A fifth cytoplasmic mutation (capr 1) obtained in Podospora anserina is described. In addition to chloramphenicol resistance it confers a strong deficiency in cytochrome aa3 and impairs the germination of ascospores. Genetic analysis shows: 1) strict maternal inheritance of (capr 1) allele; 2) selection against the (capr 1) allele as well in sexual crosses as during vegetative growth; 3) complete reversion of this selection by even low concentration of CAP. On the basis of their cytoplasmic inheritance and altered cytochrome spectra the five cytoplasmic mutations are assumed to be mitochondrial. Analysis of crosses between them allows to class them in 3 loci, 2 of which being closely linked.

MeSH Terms
Alleles Ascomycota/drug effects Chloramphenicol/pharmacology Chromosome Mapping Crosses, Genetic Drug Resistance, Microbial Genes Genetic Linkage Mitochondria/ultrastructure Mutation Recombination, Genetic
Chemicals
Chloramphenicol
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Belcour L
Begel O
References (20)
20 references, click to expand
  1. Transmission and recombination of extranuclear genes during sexual crosses in Aspergillus nidulans.
    Mol Gen Genet. 1975 Dec 30;143(1):93-9 PMID: 765748
  2. Mitochondrial antibiotic resistance in yeast: ribosomal mutants resistant to chloramphenicol, erythromycin and spiramycin.
    Biochim Biophys Acta. 1973 Jun 23;312(2):358-67 PMID: 4579232
  3. Comparison of the respiratory chain of Neurospora crassa wild type and the mi-mutants mi-1 and mi-3.
    Eur J Biochem. 1973 Feb 15;33(1):140-57 PMID: 4144164
  4. Mitochondrial genetics IX: A model for recombination and segregation of mitochondrial genomes in saccharomyces cerevisiae.
    Genetics. 1974 Sep;78(1):415-37 PMID: 4613610
  5. Cytoplasmic Mutants Selected from Continuously Growing Cultures of NEUROSPORA CRASSA.
    Genetics. 1969 Mar;61(3):643-59 PMID: 17248432
  6. Genetic evidences for a polycistronic unit of transcription in the complex locus "14" in Podospora anserina. I. Genetic and complementation maps.
    Mol Gen Genet. 1971;111(1):35-50 PMID: 5087423
  7. Induction of cyanide-insensitive respiration in Neurospora crassa.
    J Biol Chem. 1974 Jun 10;249(11):3551-6 PMID: 4275427
  8. Altered mitochondrial respiration in a chromosomal mutant of Neurospora crassa.
    J Bacteriol. 1973 Nov;116(2):610-8 PMID: 4355489
  9. Isolation and classification of extranuclear mutants of Neurospora crassa.
    Genetics. 1972 Aug;71(4):521-33 PMID: 4262391
  10. Three-marker extranuclear mitochondrial crosses in Aspergillus nidulans.
    Mol Gen Genet. 1975 Nov 3;141(1):69-79 PMID: 765725
  11. A nuclear mutation affecting structure and function of mitochondria in Paramecium.
    Mol Gen Genet. 1974 May 21;130(2):113-25 PMID: 4837325
  12. Recombination between the extranuclear genes conferring oligomycin resistance and cold sensitivity in Aspergillus nidulans.
    Mol Gen Genet. 1974;133(2):151-61 PMID: 4614065
  13. Evolution of mixed populations of genetically different mitochondria in Paramecium aurelia.
    Nature. 1972 Feb 18;235(5338):393-6 PMID: 4551646
  14. Studies on the respiratory system of the poky strain of Neurospora.
    J Biol Chem. 1953 Nov;205(1):423-33 PMID: 13117920
  15. Mitochondrial suppressor of a nuclear gene in Paramecium.
    Nature. 1975 Sep 25;257(5524):312-4 PMID: 1161033
  16. [Method for the determination of cytochrome concentrations in whole yeast cells].
    Eur J Biochem. 1970 Nov;16(3):430-8 PMID: 5477288
  17. Oxidative phosphorylation in Neurospora mitochondria. Studies on wild type, poky, and chloramphenicol-induced wild type.
    J Biol Chem. 1972 Aug 10;247(15):4859-65 PMID: 4340703
  18. Cyanide-resistant respiration in Neurospora crassa.
    J Bacteriol. 1971 Dec;108(3):1087-96 PMID: 4333318
  19. Cytoplasmic mutations isolated from protoplasts of Podospora anserina.
    Genet Res. 1975 Apr;25(2):155-61 PMID: 1183805
  20. Cytochrome abnormalities and cyanide-resistant respiration in extranuclear mutants of Aspergillus nidulans.
    J Bacteriol. 1976 Feb;125(2):389-97 PMID: 1107321
Article Info
Journal
Molecular & general genetics : MGG
Abbr.
Mol Gen Genet
ISSN
0026-8925
DOI
10.1007/BF01035991
Published
1977-05-20
Pages
11-21
Language
English
Region
Germany
NLM ID
0125036
Subset
IM
External Links
PubMed source DOI: 10.1007/BF01035991
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