The cell-mediated immune response of the pig to orally administered antigen.

Immunology ·Vol. 37 ·No. 1 ·1979-05-00 ·Pages 225-30

Huntley J, Newby TJ, Bourne FJ

Abstract

The immune response of pigs to oral immunization with dinitrophenylated bovine gamma globulin (DNP-BGG) was assessed using the indirect macrophage migration assay. Two days' exposure to the antigen resulted in the inhibition of macrophage migration by supernatants of cultures from the intestine but not the mesenteric lymph node or spleen. Stimulation for 7 days resulted in macrophage inhibition by supernatants of lymphocyte cultures prepared from the intestine, mesenteric lymph node and spleen. Supernatants of splenic lymphocytes from animals stimulated for 2 or 3 days produced enhancement of macrophage migration.

MeSH Terms

Administration, Oral Animals Antigens/administration & dosage,immunology Cell Migration Inhibition Cells, Cultured Dinitrobenzenes/immunology Immunity, Cellular Lymphocytes/immunology Macrophages/immunology Ovalbumin/administration & dosage,immunology Swine/immunology gamma-Globulins/administration & dosage,immunology

Chemicals

Antigens Dinitrobenzenes gamma-Globulins Ovalbumin

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Huntley J

Newby T J

Bourne F J

References (9)

9 references, click to expand

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Article Info

Journal

Immunology

Abbr.

Immunology

ISSN

0019-2805

Published

1979-05-00

Pages

225-30

Language

English

Region

England

NLM ID

0374672

PMCID

PMC1457283

Subset

External Links

PubMed source PMC Full Text View journal details

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The cell-mediated immune response of the pig to orally administered antigen.

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