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PMID: 8978055 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Zygotic lethal mutations with maternal effect phenotypes in Drosophila melanogaster. II. Loci on the second and third chromosomes identified by P-element-induced mutations.

Genetics ·Vol. 144 ·No. 4 ·1996-12-00 ·Pages 1681-92

Perrimon N, Lanjuin A, Arnold C, Noll E

Abstract

Screens for zygotic lethal mutations that are associated with specific maternal effect lethal phenotypes have only been conducted for the X chromosome. To identify loci on the autosomes, which represent four-fifths of the Drosophila genome, we have used the autosomal "FLP-DFS" technique to screen a collection of 496 P element-induced mutations established by the Berkeley Drosophila Genome Project. We have identified 64 new loci whose gene products are required for proper egg formation or normal embryonic development.

MeSH Terms
Animals Chromosome Mapping DNA Transposable Elements/genetics Drosophila melanogaster/genetics Genetic Techniques Mutation Phenotype
Chemicals
DNA Transposable Elements
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Perrimon N
Department of Genetics, Howard Hughes Medical Institute, Harvard Medical School, Boston, Massachusetts 02115, USA. [email protected]
Lanjuin A
Arnold C
Noll E
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Article Info
Journal
Genetics
Abbr.
Genetics
ISSN
0016-6731
DOI
10.1093/genetics/144.4.1681
Email
[email protected]
Published
1996-12-00
Pages
1681-92
Language
English
Region
United States
NLM ID
0374636
PMCID
PMC1207719
Subset
IM
External Links
PubMed source DOI: 10.1093/genetics/144.4.1681 PMC Full Text View journal details
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