Reciprocal 8;14 translocation in EBV-negative B-cell acute lymphocytic leukemia with Burkitt-type cells.

International journal of cancer ·Vol. 24 ·No. 1 ·1979-07-15 ·Pages 27-33

Mitelman F, Andersson-Anvret M, Brandt L, Catovsky D, Klein G, Manolov G, Manolova Y, Mark-Vendel E, Nilsson PG

Abstract

A cytogenetic study, including prophase-prometaphase chromosome analysis, of a patient with EBV-genome-negative acute lymphocytic leukemia of B-cell type with Burkitt-type cells is presented. All bone-marrow mitoses examined had a 14q+ marker chromosome which was identified as a reciprocal 8;14 translocation of exactly the same type as in Burkitt's lymphoma.

MeSH Terms

Antigens, Viral B-Lymphocytes/immunology Bone Marrow/pathology Burkitt Lymphoma/genetics Chromosomes, Human, 13-15 Chromosomes, Human, 6-12 and X DNA, Viral Epitopes Herpesvirus 4, Human/immunology Humans Leukemia, Lymphoid/genetics,immunology,microbiology Male Metaphase Middle Aged Nucleic Acid Hybridization Prophase Receptors, Antigen, B-Cell Translocation, Genetic

Chemicals

Antigens, Viral DNA, Viral Epitopes Receptors, Antigen, B-Cell

Authors & Affiliations

9 authors, click to expand affiliations / ORCID

Mitelman F

Andersson-Anvret M

Brandt L

Catovsky D

Klein G

Manolov G

Manolova Y

Mark-Vendel E

Nilsson P G

Article Info

Journal

International journal of cancer

Abbr.

Int J Cancer

ISSN

0020-7136

DOI

10.1002/ijc.2910240106

Published

1979-07-15

Pages

27-33

Language

English

Region

United States

NLM ID

0042124

Subset

External Links

PubMed source DOI: 10.1002/ijc.2910240106 View journal details

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Reciprocal 8;14 translocation in EBV-negative B-cell acute lymphocytic leukemia with Burkitt-type cells.

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