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PMID: 900924 Published · ppublish English Comparative Study Journal Article

In vitro susceptibility studies with cefaclor and cephalexin.

Antimicrobial agents and chemotherapy ·Vol. 12 ·No. 2 ·1977-08-00 ·Pages 290-2

Scheld WM, Korzeniowski OM, Sande MA

Abstract

The in vitro activity of cefaclor and cephalexin against clinical isolates of four bacterial genera was compared. Both agents had a similar range of activity, but cefaclor was significantly more active by weight than cephalexin for most isolates tested.

MeSH Terms
Bacteria/drug effects Cephalexin/pharmacology Cephalosporins/pharmacology Microbial Sensitivity Tests
Chemicals
Cephalosporins Cephalexin
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Scheld W M
Korzeniowski O M
Sande M A
References (8)
8 references, click to expand
  1. Comparison of in vitro activity of cephalexin, cephradine, and cefaclor.
    Antimicrob Agents Chemother. 1977 Mar;11(3):470-4 PMID: 301005
  2. Comparative pharmacology of cefaclor and cephalexin.
    Antimicrob Agents Chemother. 1977 Aug;12(2):157-62 PMID: 900915
  3. Clinical evaluation of cephradine, a new oral cephalosporin.
    Am J Med Sci. 1974 Feb;267(2):111-6 PMID: 4595266
  4. Cephradine. Antibacterial activity and clinical effectiveness.
    Chemotherapy. 1973;18(3):191-204 PMID: 4684646
  5. Estimating savings from hospital merger.
    Health Serv Res. 1972 Fall;7(3):231-8 PMID: 5072862
  6. Detailed methodology and implementation of a semiautomated serial dilution microtechnique for antimicrobial susceptibility testing.
    Appl Microbiol. 1970 Jul;20(1):46-53 PMID: 4917462
  7. Drug therapy: The newer cephalosporins.
    N Engl J Med. 1976 Jan 1;294(1):24-8 PMID: 1105179
  8. The in vitro spectrum of the cephalosporins.
    Mayo Clin Proc. 1976 Apr;51(4):237-50 PMID: 1263595
Article Info
Journal
Antimicrobial agents and chemotherapy
Abbr.
Antimicrob Agents Chemother
ISSN
0066-4804
Published
1977-08-00
Pages
290-2
Language
English
Region
United States
NLM ID
0315061
PMCID
PMC429901
Subset
IM
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