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PMID: 9016540 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Recent enhancements to the Blocks Database servers.

Nucleic acids research ·Vol. 25 ·No. 1 ·1997-01-01 ·Pages 222-5

Henikoff JG, Pietrokovski S, Henikoff S

Abstract

The Blocks Database contains multiple alignments of conserved regions in protein families which can be searched by e-mail ([email protected]) and World Wide Web (http://blocks.fhcrc.org/ ) servers to classify protein and nucleotide sequences. Recent enhancements to the servers include: (i) improved calculation of position-specific scoring matrices from blocks; (ii) availability of the Prints protein fingerprint database for searching in Blocks format; (iii) a representative sequence biased towards the Blocks of a protein family; (iv) a tree constructed from the Blocks of a protein family; (v) links to related World Wide Web pages for a family; and (vi) the new Local Alignment of Multiple Alignments (LAMA) method to search a block against a database of blocks.

MeSH Terms
Amino Acid Sequence Animals Base Sequence Computer Communication Networks Databases, Factual Humans Molecular Sequence Data Proteins/genetics Sequence Alignment/methods
Chemicals
Proteins
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Henikoff J G
Fred Hutchinson Cancer Research Center, 1124 Columbia Street, Seattle, WA 98104, USA.
Pietrokovski S
Henikoff S
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Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
0305-1048
DOI
10.1093/nar/25.1.222
Published
1997-01-01
Pages
222-5
Language
English
Region
England
NLM ID
0411011
PMCID
PMC146414
Subset
IM
Grants
NIGMS NIH HHS · GM29009 · United States
External Links
PubMed source DOI: 10.1093/nar/25.1.222 PMC Full Text View journal details
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