Rat bile as a convenient source of secretory IgA and free secretory component.

European journal of immunology ·Vol. 7 ·No. 8 ·1977-08-00 ·Pages 588-90

Lemaître-Coelho I, Jackson GD, Vaerman JP

Abstract

Rat hepatic bile contains three proteins as major constituents: secretory IgA (SIgA), free secretory component (FSC) and albumin. Traces of alpha-macroglobulin, transferrin, IgG and IgM are also detectable. The bile duct daily pours between 5-12 mg each of SIgA and FSC into the rat duodenum. The origin and function of these proteins in bile may represent important clues in the understanding of the SIgA system.

MeSH Terms

Animals Bile/immunology Chromatography, Gel Immunoelectrophoresis Immunoglobulin A Immunoglobulin A, Secretory Immunoglobulin Fragments Milk/immunology Rats Secretory Component

Chemicals

Immunoglobulin A Immunoglobulin A, Secretory Immunoglobulin Fragments Secretory Component

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Lemaître-Coelho I

Jackson G D

Vaerman J P

Article Info

Journal

European journal of immunology

Abbr.

Eur J Immunol

ISSN

0014-2980

DOI

10.1002/eji.1830070818

Published

1977-08-00

Pages

588-90

Language

English

Region

Germany

NLM ID

1273201

Subset

External Links

PubMed source DOI: 10.1002/eji.1830070818 View journal details

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