Linkage between phosphoglycerate kinase and Xg in a large German kindred.

Human genetics ·Vol. 38 ·No. 2 ·1977-09-22 ·Pages 217-21

Schwab AJ, Krietsch WK

Abstract

In a family with an extremely rare PGK variant, linkage with Xg was investigated. The analysis suggested that linkage might prove measurable. The estimate of the recombination fraction was 0.07 and the 90% probability limits were 0.05--0.28. The height of the antilog curve was 19.

MeSH Terms

Blood Group Antigens/genetics Genetic Linkage Humans Mathematics Pedigree Phenotype Phosphoglycerate Kinase/genetics Recombination, Genetic

Chemicals

Blood Group Antigens Phosphoglycerate Kinase

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Schwab A J

Krietsch W K

References (10)

10 references, click to expand

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Hum Hered. 1971;21(6):523-42 PMID: 5149961
Estimation of the recombination fraction in human pedigrees: efficient computation of the likelihood for human linkage studies.
Am J Hum Genet. 1974 Sep;26(5):588-97 PMID: 4422075
The detection and estimation of linkage between the genes for elliptocytosis and the Rh blood type.
Am J Hum Genet. 1956 Jun;8(2):80-96 PMID: 13313518
Hereditary deficiency of phosphoglycerate kinase: a new variant in erythrocytes and leucocytes, not associated with haemolytic anaemia.
Eur J Clin Invest. 1977 Oct;7(5):427-35 PMID: 411673
Sequential tests for the detection of linkage.
Am J Hum Genet. 1955 Sep;7(3):277-318 PMID: 13258560
Hereditary hemolytic anemia associated with phosphoglycerate kinase deficiency in erythrocytes and leukocytes. A probable X-chromosome-linked syndrome.
N Engl J Med. 1969 Mar 6;280(10):528-34 PMID: 5764452
Tentative evidence for 3--4 haematopoetic stem cells in man.
Hum Genet. 1977 Feb 11;35(2):175-83 PMID: 844863
Phosphoglycerate kinase: an X-linked polymorphism in man.
Am J Hum Genet. 1971 Jan;23(1):87-91 PMID: 5581984
Cytological mapping of human X-linked genes by use of somatic cell hybrids involving an X-autosome translocation (mouse-hamster-human X-linked markers).
Proc Natl Acad Sci U S A. 1972 Jan;69(1):69-73 PMID: 4500556
X-linkage of human phosphoglycerate kinase confirmed in man-mouse and man-Chinese hamster somatic cell hybrids.
Am J Hum Genet. 1971 Nov;23(6):614-23 PMID: 5132070

Article Info

Journal

Human genetics

Abbr.

Hum Genet

ISSN

0340-6717

DOI

10.1007/BF00527405

Published

1977-09-22

Pages

217-21

Language

English

Region

Germany

NLM ID

7613873

Subset

External Links

PubMed source DOI: 10.1007/BF00527405 View journal details

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Linkage between phosphoglycerate kinase and Xg in a large German kindred.

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