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PMID: 9141189 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Review

Type III secretion systems: machines to deliver bacterial proteins into eukaryotic cells?

Trends in microbiology ·Vol. 5 ·No. 4 ·1997-04-00 ·Pages 148-56

Lee CA

Abstract

Type III secretion systems in certain bacterial pathogens are induced upon contact with host cells and directly deliver virulence proteins into the host cell cytosol. The increasing number of Gram-negative bacterial pathogens discovered to encode type III secretion systems raises interesting questions. Are type III systems generic machines that deliver virulence proteins into host cells? Is contact with host cells a common regulatory cue for type III systems?

MeSH Terms
Bacterial Proteins/genetics,metabolism Eukaryotic Cells Gene Expression Regulation, Bacterial
Chemicals
Bacterial Proteins
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Lee C A
Dept of Microbiology and Molecular Genetics, Harvard Medical School, Boston, MA 02115, USA. [email protected]
Article Info
Journal
Trends in microbiology
Abbr.
Trends Microbiol
ISSN
0966-842X
Published
1997-04-00
Pages
148-56
Language
English
Region
England
NLM ID
9310916
Subset
IM
Grants
NIAID NIH HHS · AI33444 · United States
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