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PMID: 9160509 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Review

Apoptosis as a proinflammatory event: what can we learn from bacteria-induced cell death?

Trends in microbiology ·Vol. 5 ·No. 5 ·1997-05-00 ·Pages 201-4

Zychlinsky A, Sansonetti PJ

Abstract

Infection of cells by some pathogenic bacteria triggers host cell apoptosis. Bacteria-induced apoptosis appears to promote an inflammatory response that causes tissue damage and further bacterial colonization. Shigella pathogenesis offers a paradigm for the role of apoptosis in bacterial infections.

MeSH Terms
Apoptosis/immunology Bacterial Infections/immunology Dysentery, Bacillary/epidemiology,immunology Humans Inflammation/physiopathology Macrophages
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Zychlinsky A
Dept of Microbiology, New York University School of Medicine, NY 10016, USA. [email protected]
Sansonetti P J
Article Info
Journal
Trends in microbiology
Abbr.
Trends Microbiol
ISSN
0966-842X
DOI
10.1016/S0966-842X(97)01044-5
Email
[email protected]
Published
1997-05-00
Pages
201-4
Language
English
Region
England
NLM ID
9310916
Subset
IM
Grants
NIAID NIH HHS · AI37720 · United States
External Links
PubMed source DOI: 10.1016/S0966-842X(97)01044-5 View journal details
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