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PMID: 9180076 Published · ppublish English Comment Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Multiple and ancient origins of the domestic dog.

Science (New York, N.Y.) ·Vol. 276 ·No. 5319 ·1997-06-13 ·Pages 1687-9

Vilà C, Savolainen P, Maldonado JE, Amorim IR, Rice JE, Honeycutt RL, Crandall KA, Lundeberg J, Wayne RK

Abstract

Mitochondrial DNA control region sequences were analyzed from 162 wolves at 27 localities worldwide and from 140 domestic dogs representing 67 breeds. Sequences from both dogs and wolves showed considerable diversity and supported the hypothesis that wolves were the ancestors of dogs. Most dog sequences belonged to a divergent monophyletic clade sharing no sequences with wolves. The sequence divergence within this clade suggested that dogs originated more than 100,000 years before the present. Associations of dog haplotypes with other wolf lineages indicated episodes of admixture between wolves and dogs. Repeated genetic exchange between dog and wolf populations may have been an important source of variation for artificial selection.

MeSH Terms

Animals Base Sequence Biological Evolution Breeding Carnivora/genetics Crosses, Genetic DNA, Mitochondrial/genetics Dogs/classification,genetics Female Haplotypes Male Molecular Sequence Data Phylogeny Sequence Homology, Nucleic Acid

Chemicals

DNA, Mitochondrial

Authors & Affiliations

9 authors, click to expand affiliations / ORCID

Vilà C

Department of Biology, University of California, Los Angeles, CA 90095-1606, USA.

Savolainen P

Maldonado J E

Amorim I R

Rice J E

Honeycutt R L

Crandall K A

Lundeberg J

Wayne R K

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.276.5319.1687

Published

1997-06-13

Pages

1687-9

Language

English

Region

United States

NLM ID

0404511

Subset

Databases

GENBANK

AF005280, AF005281, AF005282, AF005283, AF005284, AF005285, AF005286, AF005287, AF005288, AF005289, AF005290, AF005291, AF005292, AF005293, AF005294, AF005295, AF005296, AF005297, AF005298, AF005299, AF005300, AF005301, AF005302, AF005303, AF005304, AF005305, AF005306

Corrections

CommentIn

PMID: 9206828

CommentIn

PMID: 9340762

CommentIn

PMID: 9340763

CommentOn

PMID: 9340763

External Links

PubMed source DOI: 10.1126/science.276.5319.1687 View journal details

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Multiple and ancient origins of the domestic dog.

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