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PMID: 9257773 Published · ppublish English Comparative Study Journal Article Research Support, Non-U.S. Gov't

In vitro evaluation of voriconazole against some clinically important fungi.

Antimicrobial agents and chemotherapy ·Vol. 41 ·No. 8 ·1997-08-00 ·Pages 1832-4

McGinnis MR, Pasarell L, Sutton DA, Fothergill AW, Cooper CR, Rinaldi MG

Abstract

Voriconazole was compared to amphotericin B, fluconazole, and itraconazole by using an in vitro macrobroth dilution test based upon current National Committee for Clinical Laboratory Standards tentative standards against the dimorphic fungi and several opportunistic molds and yeasts. In all instances, the voriconazole MICs were lower than those of fluconazole. In most instances, the MICs were lower than the recorded MICs of amphotericin B and itraconazole.

MeSH Terms
Antifungal Agents/pharmacology Evaluation Studies as Topic Fungi/drug effects In Vitro Techniques Microbial Sensitivity Tests Pyrimidines/pharmacology Triazoles/pharmacology Voriconazole
Chemicals
Antifungal Agents Pyrimidines Triazoles Voriconazole
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
McGinnis M R
Department of Pathology and WHO Collaborating Center for Tropical Diseases, University of Texas Medical Branch, Galveston 77555-0609, USA.
Pasarell L
Sutton D A
Fothergill A W
Cooper C R
Rinaldi M G
References (6)
6 references, click to expand
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Article Info
Journal
Antimicrobial agents and chemotherapy
Abbr.
Antimicrob Agents Chemother
ISSN
0066-4804
DOI
10.1128/AAC.41.8.1832
Published
1997-08-00
Pages
1832-4
Language
English
Region
United States
NLM ID
0315061
PMCID
PMC164017
Subset
IM
External Links
PubMed source DOI: 10.1128/AAC.41.8.1832 PMC Full Text View journal details
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