Celiac disease and selective immunoglobulin A deficiency.

The Journal of pediatrics ·Vol. 131 ·No. 2 ·1997-08-00 ·Pages 306-8

Cataldo F, Marino V, Bottaro G, Greco P, Ventura A

Abstract

Selective IgA deficiency was observed in 12 of 688 (1.7%) patients with celiac disease who were clinically undistinguishable from patients with celiac disease with normal IgA levels. This high prevalence of IgA deficiency in patients with celiac disease makes serum IgA assay advisable when screening for celiac disease is performed by measurement of antigliadin antibodies or anti-IgA endomysium antibodies. Similarly, subjects with IgA deficiency should be considered at risk of celiac disease.

MeSH Terms

Adolescent Age Factors Celiac Disease/complications,diet therapy,immunology Chi-Square Distribution Child Child, Preschool Confidence Intervals Cross-Sectional Studies Diet, Protein-Restricted Follow-Up Studies Gliadin/immunology Glutens/administration & dosage Humans IgA Deficiency/blood,complications Immunoglobulin A/blood Immunoglobulin G/blood Immunoglobulin M/blood Infant Intestinal Diseases/complications,immunology Muscle Fibers, Skeletal/immunology Myofibrils/immunology Prevalence Risk Factors

Chemicals

Immunoglobulin A Immunoglobulin G Immunoglobulin M Glutens Gliadin

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Cataldo F

Seconda Clinica Pediatrica, University of Palermo, Italy.

Marino V

Bottaro G

Greco P

Ventura A

Article Info

Journal

The Journal of pediatrics

Abbr.

J Pediatr

ISSN

0022-3476

DOI

10.1016/s0022-3476(97)70172-0

Published

1997-08-00

Pages

306-8

Language

English

Region

United States

NLM ID

0375410

Subset

External Links

PubMed source DOI: 10.1016/s0022-3476(97)70172-0 View journal details

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