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PMID: 9335600 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

The sex-ratio trait in Drosophila simulans: genetic analysis of distortion and suppression.

Genetics ·Vol. 147 ·No. 2 ·1997-10-00 ·Pages 635-42

Cazemajor M, Landré C, Montchamp-Moreau C

Abstract

The sex-ratio trait described in several Drosophila species is a type of naturally occurring X-linked meiotic drive that causes males bearing a sex-ratio X chromosome to produce progenies with a large excess of females. We have previously reported the occurrence of sex-ratio X chromosomes in Drosophila simulans. In this species, because of the co-occurrence of drive suppressors, the natural populations and the derived laboratory strains show an equal sex-ratio even when sex-ratio X chromosomes are present at a high frequency. The presence of sex-ratio X chromosomes is established via crosses with a standard strain that is devoid of drive suppressors. In this article, we show first that the sex-ratio trait in D. simulans results from the action of several X-linked loci. Second we describe drive suppressors on each major autosome as well as on the Y chromosome. The Y-linked factors suppress the drive partially whereas the autosomal suppression can be complete.

MeSH Terms
Animals Chromosome Mapping Drosophila/genetics Female Genes, Suppressor Male Sex Ratio X Chromosome
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Cazemajor M
Institut Jacques Monod, Laboratoire Dynamique du Génome et Evolution, CNRS-Université Paris, France.
Landré C
Montchamp-Moreau C
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Article Info
Journal
Genetics
Abbr.
Genetics
ISSN
0016-6731
DOI
10.1093/genetics/147.2.635
Published
1997-10-00
Pages
635-42
Language
English
Region
United States
NLM ID
0374636
PMCID
PMC1208185
Subset
IM
External Links
PubMed source DOI: 10.1093/genetics/147.2.635 PMC Full Text View journal details
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