Home LiteratureArticle Details
PMID: 934023 Published · ppublish English Journal Article

Some properties of coagulase-negative deoxyribonuclease-producing strains of staphylococci from human infections.

Medical microbiology and immunology ·Vol. 162 ·No. 2 ·1976-06-01 ·Pages 143-52

Dornbusch K, Nord CE, Olsson B, Wadström T

Abstract

Twenty-seven coagulase-negative and deoxyribonuclease-positive staphylococci were isolated from more than 3000 specimens from human infections. The strains were tested by conventional biochemical tests and by simple agar plate assays for production of different extracellular enzymes and toxins. Three strains were lysed by S. epidermidis phages and 7 strains by S. aureus phages. All strains produced thermolabile nuclease but only 21 strains produced thermostable nuclease. The investigated strains belonged to a heterogeneous intermediate group sharing characters of S. aureus and S. epidermidis. Tests for production of coagulase and thermostable nuclease should be used in the classification of these intermediate strains in diagnostic bacteriology.

MeSH Terms
Bacteriophage Typing Coagulase/biosynthesis Deoxyribonucleases/biosynthesis Humans Staphylococcal Infections/microbiology Staphylococcus/enzymology Staphylococcus aureus/enzymology
Chemicals
Coagulase Deoxyribonucleases
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Dornbusch K
Nord C E
Olsson B
Wadström T
References (37)
37 references, click to expand
  1. Production of enzymes and toxins by hospital strains of Pseudomonas aeruginosa in relation to serotype and phage-typing pattern.
    J Med Microbiol. 1973 Feb;6(1):91-100 PMID: 4632256
  2. Characters of phages from coagulase-negative staphylococci.
    J Med Microbiol. 1971 Nov;4(4):413-24 PMID: 4257496
  3. Phosphatase reaction of coagulase-negative staphylococci and micrococci.
    J Pathol Bacteriol. 1967 Apr;93(2):685-8 PMID: 4293310
  4. Detection of nuclease activity in semisolid and broth cultures.
    Appl Microbiol. 1969 Aug;18(2):174-6 PMID: 4185235
  5. Coagulase and deoxyribonuclease activities of staphylococci isolated from clinical sources.
    Appl Microbiol. 1972 Apr;23 (4):725-33 PMID: 4336228
  6. Bacteriolytic enzymes from staphylococci.
    Contrib Microbiol Immunol. 1973;1:397-405 PMID: 4805314
  7. Isolation of mutants of Staphylococcus aureus lacking extracellular nuclease activity.
    J Bacteriol. 1970 Mar;101(3):921-4 PMID: 4985592
  8. Desoxyribonuclease and coagulase activity of micrococci.
    Med Techn Bull. 1958 Sep-Oct;9(5):191-6 PMID: 13577185
  9. Staphylococcus epidermidis isolated from bovine milk. Biochemical properties, phage sensitivity and pathogenicity for the udder.
    Acta Vet Scand Suppl. 1973;:1-144 PMID: 4358805
  10. Frequency of staphylococcal lysozyme production tested by plate method.
    J Clin Pathol. 1968 May;21(3):390-3 PMID: 4880766
  11. Phage typing of staphylococci.
    Bull World Health Organ. 1961;24(6):771-84 PMID: 20604092
  12. Importance of coagulase-negative staphylococci as pathogens in the urinary tract.
    Lancet. 1974 Jun 8;1(7867):1155-8 PMID: 4136804
  13. Comparison of animal sera for suitability in coagulase testing.
    Appl Microbiol. 1971 Mar;21(3):420-5 PMID: 4251847
  14. Lysozyme production as an aid for identification of potentially pathogenic strains of staphylococci.
    Appl Microbiol. 1968 Nov;16(11):1745-7 PMID: 5749750
  15. Nuclease production and lysostaphin susceptibility of Staphylococcus aureus and other catalase-positive cocci.
    Appl Microbiol. 1971 May;21(5):823-6 PMID: 5574317
  16. Pathogenicity of Staphylococcus aureus mutants in general and local infections.
    Acta Pathol Microbiol Scand B Microbiol Immunol. 1972;80(4):564-70 PMID: 4264698
  17. A serological method for distinguishing coagulase-negative staphylococci from micrococci.
    J Clin Pathol. 1973 Jul;26(7):511-6 PMID: 4737863
  18. Penicillinase production and intrinsic resistance to penicillins in Staphylococcus aures.
    Lancet. 1966 Apr 16;1(7442):835-8 PMID: 4159958
  19. Significance of protein a production by staphylococci.
    Infect Immun. 1970 Nov;2(5):672-3 PMID: 16557894
  20. The relationship of pathogenic coagulase-negative staphylococci to Staphylococcus aureus.
    Can J Microbiol. 1969 Aug;15(8):879-90 PMID: 5344740
  21. PRODUCTION OF LARGE QUANTITIES OF ENTEROTOXIN B AND OTHER STAPHYLOCOCCAL TOXINS ON SOLID MEDIA.
    Acta Pathol Microbiol Scand. 1965;63:299-305 PMID: 14295449
  22. Antibiotic sensitivity testing. Report of an international collaborative study.
    Acta Pathol Microbiol Scand B Microbiol Immunol. 1971;217:Suppl 217:1+ PMID: 4325956
  23. The taxonomic significance of fermentative versus oxidative metabolism of carbohydrates by various gram negative bacteria.
    J Bacteriol. 1953 Jul;66(1):24-6 PMID: 13069461
  24. THE CLASSIFICATION OF STAPHYLOCOCCI AND MICROCOCCI FROM WORLD-WIDE SOURCES.
    J Gen Microbiol. 1965 Mar;38:363-87 PMID: 14329964
  25. COAGULASE-NEGATIVE MUTANTS OF STAPHYLOCOCCUS AUREUS: GENETIC STUDIES.
    J Bacteriol. 1963 Sep;86:363-9 PMID: 14066411
  26. Studies in urinary tract infections. 3. Biochemical characteristics of coagulase-negative staphylococci associated with urinary tract infections.
    Acta Med Scand. 1969 Jul-Aug;186(1-2):47-51 PMID: 4241227
  27. Protein A mutants of Staphylococcus aureus.
    J Bacteriol. 1971 Jul;107(1):245-50 PMID: 4254663
  28. Intraspecific transduction in Staphylococcus epidermidis and interspecific transduction between Staphylococcus aureus and Staphylococcus epidermidis.
    Can J Microbiol. 1971 Jun;17(6):767-73 PMID: 4253231
  29. Bacteriolytic enzymes from Staphylococcus aureus. Purification of an endo-beta-N-acetylglucosaminidase.
    Biochem J. 1970 Dec;120(4):725-34 PMID: 4992953
  30. The detection of methicillin resistance in Staphylococcus aureus.
    J Med Microbiol. 1969 Nov 4;2(4):443-56 PMID: 5404802
  31. Relationships among coagulase, enterotoxin, and heat-stable deoxyribonuclease production by Staphylococcus aureus.
    Appl Microbiol. 1969 Jul;18(1):126-7 PMID: 4896099
  32. Transfer of tetracycline-resistance between strains of Staphylococcus aureus in mixed cultures.
    J Gen Microbiol. 1971 Dec;69(2):229-37 PMID: 4259861
  33. Coagulase-negative staphylococci and micrococci in urinary tract infections.
    J Clin Pathol. 1975 Apr;28(4):270-3 PMID: 1127120
  34. Modification of Baird-Parker's classification system of Staphylococcus albus.
    Med Microbiol Immunol. 1973;158(4):249-57 PMID: 4354970
  35. Toxins and enzymes of coagulase negative staphylococci isolated from human infections.
    J Hyg Epidemiol Microbiol Immunol. 1974;18(3):276-80 PMID: 4371316
  36. A simple diagnostic milk medium for Pseudomonas aeruginosa.
    J Clin Pathol. 1970 Mar;23(2):172-7 PMID: 4987392
  37. FRACTIONATION OF STAPHYLOCOCCAL TOXINS BY GEL-FILTRATION.
    Acta Pathol Microbiol Scand. 1963;59:543-52 PMID: 14080488
Article Info
Journal
Medical microbiology and immunology
Abbr.
Med Microbiol Immunol
ISSN
0300-8584
DOI
10.1007/BF02121324
Published
1976-06-01
Pages
143-52
Language
English
Region
Germany
NLM ID
0314524
Subset
IM
External Links
PubMed source DOI: 10.1007/BF02121324 View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2