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PMID: 9399843 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

The Androgen Receptor Gene Mutations Database.

Nucleic acids research ·Vol. 26 ·No. 1 ·1998-01-01 ·Pages 234-8

Gottlieb B, Lehvaslaiho H, Beitel LK, Lumbroso R, Pinsky L, Trifiro M

Abstract

The current version of the androgen receptor (AR) gene mutations database is described. The total number of reported mutations has risen from 272 to 309 in the past year. We have expanded the database: (i) by giving each entry an accession number; (ii) by adding information on the length of polymorphic polyglutamine (polyGln) and polyglycine (polyGly) tracts in exon 1; (iii) by adding information on large gene deletions; (iv) by providing a direct link with a completely searchable database (courtesy EMBL-European Bioinformatics Institute). The addition of the exon 1 polymorphisms is discussed in light of their possible relevance as markers for predisposition to prostate or breast cancer. The database is also available on the internet (http://www.mcgill. ca/androgendb/ ), from EMBL-European Bioinformatics Institute (ftp. ebi.ac.uk/pub/databases/androgen ), or as a Macintosh FilemakerPro or Word file ([email protected]).

MeSH Terms

Computer Communication Networks Databases, Factual Humans Mutation Receptors, Androgen/genetics

Chemicals

Receptors, Androgen

Authors & Affiliations

6 authors, click to expand affiliations / ORCID

Gottlieb B

Lady Davis Institute for Medical Research, Sir Mortimer B. Davis-Jewish General Hospital, McGill University, 3755 Chemin de la Cote-Ste-Catherine, Montreal, Quebec H3T 1E2, Canada. [email protected]

Lehvaslaiho H

Beitel L K

Lumbroso R

Pinsky L

Trifiro M

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23 references, click to expand

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Article Info

Journal

Nucleic acids research

Abbr.

Nucleic Acids Res

ISSN

0305-1048

DOI

10.1093/nar/26.1.234

[email protected]

Published

1998-01-01

Pages

234-8

Language

English

Region

England

NLM ID

0411011

PMCID

PMC147184

Subset

Grants

Wellcome Trust · United Kingdom

External Links

PubMed source DOI: 10.1093/nar/26.1.234 PMC Full Text View journal details

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