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PMID: 9424 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Immune response to acute otitis media: association between middle ear fluid antibody and the clearing of clinical infection.

Journal of clinical microbiology ·Vol. 4 ·No. 3 ·1976-09-00 ·Pages 306-8

Sloyer JL, Howie VM, Ploussard JH, Schiffman G, Johnston RB

Abstract

Clearing of the middle ear fluid in patients with acute otitis media due to Streptococcus pneumoniae or Haemophilus influenzae was significantly associated with the presence and concentration of specific antibody in the middle ear fluid at the time of diagnosis.

MeSH Terms
Antibodies, Bacterial/analysis Body Fluids/immunology Child, Preschool Ear, Middle Haemophilus Infections/immunology Haemophilus influenzae/immunology Humans Immunoglobulin A/analysis Immunoglobulin G/analysis Immunoglobulin M/analysis Infant Otitis Media/immunology Pneumococcal Infections/immunology Streptococcus pneumoniae/immunology
Chemicals
Antibodies, Bacterial Immunoglobulin A Immunoglobulin G Immunoglobulin M
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Sloyer J L
Howie V M
Ploussard J H
Schiffman G
Johnston R B
References (10)
10 references, click to expand
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  2. Secretory immunoglobulin A (SIgA) in middle ear effusions. Observation of 160 specimens.
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    J Immunol. 1969 Aug;103(2):215-24 PMID: 4184822
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    J Immunol. 1974 Feb;112(2):488-95 PMID: 4205203
  7. The "in vivo sensitivity test"--bacteriology of middle ear exudate, during antimicrobial therapy in otitis media.
    Pediatrics. 1969 Dec;44(6):940-4 PMID: 4391491
  8. The morphological basis for understanding middle ear effusions. An electron microscopic, cytochemical, and autoradiographic investigation.
    Laryngoscope. 1972 Sep;82(9):1625-42 PMID: 4562534
  9. Serous otitis media. Immunoglobulin and lysozyme levels in middle ear fluids and serum.
    Ann Otol Rhinol Laryngol. 1973 May-Jun;82(3):297-301 PMID: 4712166
  10. Effect of physical state and route of inoculation of diphtheria toxoid on the formation of nasal secretory and serum antibodies in man.
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Article Info
Journal
Journal of clinical microbiology
Abbr.
J Clin Microbiol
ISSN
0095-1137
DOI
10.1128/jcm.4.3.306-308.1976
Published
1976-09-00
Pages
306-8
Language
English
Region
United States
NLM ID
7505564
PMCID
PMC274454
Subset
IM
External Links
PubMed source DOI: 10.1128/jcm.4.3.306-308.1976 PMC Full Text View journal details
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