Mitotic arrest: Mad2 prevents sleepy from waking up the APC.

Anaphase Anaphase-Promoting Complex-Cyclosome Calcium-Binding Proteins/metabolism Carrier Proteins/metabolism Cdc20 Proteins Cell Cycle Proteins/antagonists & inhibitors,metabolism Fungal Proteins/antagonists & inhibitors,metabolism Ligases/metabolism Mad2 Proteins Mitosis Models, Biological Nuclear Proteins/metabolism Saccharomyces cerevisiae/cytology,metabolism Saccharomyces cerevisiae Proteins Schizosaccharomyces/cytology,metabolism Schizosaccharomyces pombe Proteins Securin Spindle Apparatus/metabolism Ubiquitin-Protein Ligase Complexes Ubiquitin-Protein Ligases

CDC20 protein, S cerevisiae Calcium-Binding Proteins Carrier Proteins Cdc20 Proteins Cell Cycle Proteins Cut2 protein, S pombe Fungal Proteins MAD2 protein, S cerevisiae Mad2 Proteins Nuclear Proteins PDS1 protein, S cerevisiae Saccharomyces cerevisiae Proteins Schizosaccharomyces pombe Proteins Securin mad2 protein, S pombe slp1 protein, S pombe Ubiquitin-Protein Ligase Complexes Anaphase-Promoting Complex-Cyclosome Ubiquitin-Protein Ligases Ligases