Myb proteins in life, death and differentiation.

Current opinion in genetics & development ·Vol. 8 ·No. 1 ·1998-02-00 ·Pages 76-81

Weston K

Abstract

Myb transcription factors are crucial to the control of proliferation and differentiation in a number of cell types but their mechanism of action is unclear. Regulation of Myb proteins by phosphorylation and intermolecular cooperation has recently been demonstrated, together with a new role for the proteins, in the control of apoptosis.

MeSH Terms

Animals Cell Cycle Proteins Cell Death Cell Differentiation Cell Survival DNA-Binding Proteins/genetics,physiology Humans Proto-Oncogene Proteins/genetics,physiology Proto-Oncogene Proteins c-myb Trans-Activators/genetics,physiology Transcription Factors/genetics,physiology

Chemicals

Cell Cycle Proteins DNA-Binding Proteins MYBL1 protein, human MYBL2 protein, human Proto-Oncogene Proteins Proto-Oncogene Proteins c-myb Trans-Activators Transcription Factors

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Weston K

CRC Centre for Cell and Molecular Biology, Chester Beatty Laboratories, London, UK. [email protected]

Article Info

Journal

Current opinion in genetics & development

Abbr.

Curr Opin Genet Dev

ISSN

0959-437X

DOI

10.1016/s0959-437x(98)80065-8

[email protected]

Published

1998-02-00

Pages

76-81

Language

English

Region

England

NLM ID

9111375

Subset

External Links

PubMed source DOI: 10.1016/s0959-437x(98)80065-8 View journal details

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