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PMID: 954982 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Epidermal growth factor enhancement of skin tumor induction in mice.

Experientia ·Vol. 32 ·No. 7 ·1976-00-00 ·Pages 913-5

Rose SP, Stahn R, Passovoy DS, Herschman H

Abstract

Subcutaneous injection of epidermal growth factor 1. significantly shortened the latency period for the appearance of methylcholanthrene induced skin tumors and 2. increased the average number of papillomas elicited per mouse in both the Swiss Webster and C3HeB/FeJ strains.

MeSH Terms
Animals Female Growth Substances Methylcholanthrene Mice Mice, Inbred C3H Papilloma/chemically induced Peptides Skin Neoplasms/chemically induced Time Factors
Chemicals
Growth Substances Peptides Methylcholanthrene
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Rose S P
Stahn R
Passovoy D S
Herschman H
References (13)
13 references, click to expand
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  9. THE INITIATING AND PROMOTING ELEMENTS IN TUMOR PRODUCTION : AN ANALYSIS OF THE EFFECTS OF TAR, BENZPYRENE, AND METHYLCHOLANTHRENE ON RABBIT SKIN.
    J Exp Med. 1944 Aug 1;80(2):101-26 PMID: 19871401
  10. Studies on the mechanism of skin tumor promotion.
    Cancer Res. 1970 Feb;30(2):312-20 PMID: 5458969
  11. The tumor-enhancing principles of Croton tiglium L.
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Article Info
Journal
Experientia
Abbr.
Experientia
ISSN
0014-4754
Published
1976-00-00
Pages
913-5
Language
English
Region
Switzerland
NLM ID
0376547
Subset
IM
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