Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma.

Animals CD36 Antigens/analysis,genetics Cell Differentiation Cells, Cultured Dimerization Fatty Acids, Unsaturated/pharmacology Humans Ligands Linoleic Acids/metabolism,pharmacology Linoleic Acids, Conjugated Lipopolysaccharide Receptors/analysis Lipoproteins, LDL/metabolism,pharmacology Macrophages/metabolism Membrane Proteins Monocytes/cytology,metabolism Oxidation-Reduction Prostaglandin D2/analogs & derivatives,pharmacology Receptors, Cytoplasmic and Nuclear/chemistry,genetics,metabolism Receptors, Immunologic/genetics Receptors, Lipoprotein Receptors, Retinoic Acid/chemistry,metabolism Receptors, Scavenger Recombinant Fusion Proteins Retinoid X Receptors Scavenger Receptors, Class B Signal Transduction/physiology Transcription Factors/chemistry,genetics,metabolism Transcriptional Activation/physiology

15-deoxy-delta(12,14)-prostaglandin J2 CD36 Antigens Fatty Acids, Unsaturated Ligands Linoleic Acids Linoleic Acids, Conjugated Lipopolysaccharide Receptors Lipoproteins, LDL Membrane Proteins Receptors, Cytoplasmic and Nuclear Receptors, Immunologic Receptors, Lipoprotein Receptors, Retinoic Acid Receptors, Scavenger Recombinant Fusion Proteins Retinoid X Receptors Scarb1 protein, mouse Scavenger Receptors, Class B Transcription Factors oxidized low density lipoprotein 9-hydroxy-10,12-octadecadienoic acid 13-hydroxy-9,11-octadecadienoic acid Prostaglandin D2