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PMID: 963733 Published · ppublish English Journal Article

The ultrastructure of paraganglia associated with the inferior mesenteric ganglia in the guinea-pig.

Cell and tissue research ·Vol. 171 ·No. 1 ·1976-08-16 ·Pages 123-39

Furness JB, Sobels G

Abstract

The paraganglia of the inferior mesenteric ganglia in the guinea-pig are composed of small chromaffin cells containing an abundance of granule-containing vesicles. The chromaffin cells are almost completely surrounded by satellite cells. In areas in which satellite cell processes do not intervene, the membranes of adjacent chromaffin cells are closely apposed and often form specialized attachment zones. The paraganglia contain a dense capillary network, the endothelial cells of which are often extremely attenuated and show areas of fenestration. The processes of chromaffin cells approach close to the capillary walls and are often bare of satellite cells covering on the side facing the capillary. Evidence has been obtained for the exocytotic release of the contents of chromaffin cell vesicles into pericapillary spaces. Synapses of cholinergic and noradrenergic axons are seen on the chromaffin cells. The cholinergic axons degenerate when the praganglia are decentralized, but the noradrenergic axons, which appear to arise from the local inferior mesenteric ganglia, remain intact. The results suggest that the paraganglia have an endocrine function.

MeSH Terms
Animals Axons/ultrastructure Capillaries/ultrastructure Chromaffin System/ultrastructure Ganglia, Autonomic/ultrastructure Guinea Pigs Interneurons Mesentery/innervation Norepinephrine Paraganglia, Chromaffin/blood supply,ultrastructure Parasympathetic Nervous System Synapses/ultrastructure
Chemicals
Norepinephrine
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Furness J B
Sobels G
References (40)
40 references, click to expand
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Article Info
Journal
Cell and tissue research
Abbr.
Cell Tissue Res
ISSN
0302-766X
DOI
10.1007/BF00219704
Published
1976-08-16
Pages
123-39
Language
English
Region
Germany
NLM ID
0417625
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00219704 View journal details
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