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PMID: 9658024 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

General stress transcription factor sigmaB and sporulation transcription factor sigmaH each contribute to survival of Bacillus subtilis under extreme growth conditions.

Journal of bacteriology ·Vol. 180 ·No. 14 ·1998-07-00 ·Pages 3730-3

Gaidenko TA, Price CW

Abstract

The general stress response of the bacterium Bacillus subtilis is controlled by the sigmaB transcription factor. Here we show that loss of sigmaB reduces stationary-phase viability 10-fold in either alkaline or acidic media and reduces cell yield in media containing ethanol. We further show that loss of the developmental transcription factor sigmaH also has a marked effect on stationary-phase viability under these conditions and that this effect is independent from the simple loss of sporulation ability.

MeSH Terms
Anti-Infective Agents, Local/pharmacology Bacillus subtilis/cytology,drug effects,physiology Bacterial Proteins/drug effects,physiology Cell Division/drug effects,physiology Colony Count, Microbial Ethanol/pharmacology Hydrogen-Ion Concentration Sigma Factor/drug effects,physiology Spores, Bacterial/genetics Transcription Factors/physiology
Chemicals
Anti-Infective Agents, Local Bacterial Proteins SigB protein, Bacteria Sigma Factor Transcription Factors Ethanol
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Gaidenko T A
Department of Food Science and Technology, University of California, Davis, California 95616, USA.
Price C W
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/JB.180.14.3730-3733.1998
Published
1998-07-00
Pages
3730-3
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC107349
Subset
IM
Grants
NIGMS NIH HHS · R01 GM042077 · United States
NIGMS NIH HHS · GM42077 · United States
External Links
PubMed source DOI: 10.1128/JB.180.14.3730-3733.1998 PMC Full Text View journal details
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