Heat shock and apoptosis. The two defense systems of the organism may have overlapping molecular elements.

Annals of the New York Academy of Sciences ·Vol. 851 ·1998-06-30 ·Pages 67-74

Punyiczki M, Fésüs L

Abstract

Stress response and apoptosis are two interrelated end points of the defense systems of living organisms. The molecular elements of the two have strong influences on each other. Ceramide formation and signal-induced phosphorylation cascades may be critical in determining the final fate of cells exposed to environmental changes.

MeSH Terms

Apoptosis/drug effects,physiology Calcium-Calmodulin-Dependent Protein Kinases/metabolism Ceramides/metabolism Heat-Shock Proteins/physiology Molecular Chaperones/physiology Phosphorylation

Chemicals

Ceramides Heat-Shock Proteins Molecular Chaperones Calcium-Calmodulin-Dependent Protein Kinases

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Punyiczki M

Department of Biochemistry and Molecular Biology, University Medical School of Debrecen, Hungary. [email protected]

Fésüs L

Article Info

Journal

Annals of the New York Academy of Sciences

Abbr.

Ann N Y Acad Sci

ISSN

0077-8923

DOI

10.1111/j.1749-6632.1998.tb08978.x

[email protected]

Published

1998-06-30

Pages

67-74

Language

English

Region

United States

NLM ID

7506858

Subset

External Links

PubMed source DOI: 10.1111/j.1749-6632.1998.tb08978.x View journal details

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Heat shock and apoptosis. The two defense systems of the organism may have overlapping molecular elements.

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