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PMID: 967244 Published · ppublish English Journal Article

Rolling hairpin model for replication of parvovirus and linear chromosomal DNA.

Nature ·Vol. 263 ·No. 5573 ·1976-09-09 ·Pages 106-9

Tattersall P, Ward DC

Abstract

A novel, quasicircular scheme is proposed for the replication of parvovirus DNA. Daughter strands are initiated after the copying and rearrangement of a terminal palindromic sequence, a process termed 'hairpin transfer'. Such a process may be involved in the replication of other viruses and host cell DNA.

MeSH Terms
Base Sequence Chromosomes/metabolism DNA Replication DNA, Single-Stranded/biosynthesis,metabolism DNA, Viral/biosynthesis,metabolism Minute Virus of Mice/metabolism Models, Biological Parvoviridae/metabolism Virus Replication
Chemicals
DNA, Single-Stranded DNA, Viral
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Tattersall P
Ward D C
Article Info
Journal
Nature
Abbr.
Nature
ISSN
0028-0836
DOI
10.1038/263106a0
Published
1976-09-09
Pages
106-9
Language
English
Region
England
NLM ID
0410462
Subset
IM
External Links
PubMed source DOI: 10.1038/263106a0 View journal details
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