Gene conversion: a hitherto overlooked parameter in population genetics.

Genetics ·Vol. 83 ·No. 4 ·1976-08-00 ·Pages 861-6

Gutz H, Leslie JF

Abstract

Gene conversion causes deviations from the 2:2 segregation of allele pairs in meiosis. Thus, gene conversion is a potential cause for changes of allele frequencies in populations. Equations are derived for the effects of conversion in a large random-mating population. The influence of gene conversion on allele frequencies is compared with that of spontaneous mutation and meiotic drive.

MeSH Terms

Alleles Gene Frequency Genes Genetics, Population Meiosis Models, Biological Recombination, Genetic

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Gutz H

Leslie J F

References (4)

4 references, click to expand

Gene conversion and transfer of genetic information within the inverted region of inversion heterozygotes.
Genetics. 1973 Sep;75(1):123-31 PMID: 4202769
Gene conversion in higher organisms: non-reciprocal recombination events at the rosy cistron in Drosophila melanogaster.
Genet Res. 1971 Apr;17(2):139-49 PMID: 4999444
Studies on gene conversion and its relationship to linked exchange in Drosophila melanogaster.
Genetics. 1971 Oct;69(2):179-209 PMID: 5002749
Site Specific Induction of Gene Conversion in SCHIZOSACCHAROMYCES POMBE.
Genetics. 1971 Nov;69(3):317-37 PMID: 17248549

Article Info

Journal

Genetics

Abbr.

Genetics

ISSN

0016-6731

DOI

10.1093/genetics/83.4.861

Published

1976-08-00

Pages

861-6

Language

English

Region

United States

NLM ID

0374636

PMCID

PMC1213556

Subset

External Links

PubMed source DOI: 10.1093/genetics/83.4.861 PMC Full Text View journal details

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