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PMID: 97232 Published · ppublish English Comparative Study Journal Article

Relationship of method of administration to respiratory virulence of Klebsiella pneumoniae for mice and squirrel monkeys.

Infection and immunity ·Vol. 20 ·No. 2 ·1978-05-00 ·Pages 581-3

Berendt RF

Abstract

Klebsiella pneumoniae given by aerosol was significantly less virulent in mice and monkeys than when given by intranasal (mice) or intratracheal (monkeys) instillation.

MeSH Terms
Administration, Intranasal Aerosols Animals Haplorhini Intubation, Intratracheal Klebsiella Infections/microbiology Klebsiella pneumoniae/pathogenicity Mice Saimiri
Chemicals
Aerosols
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Berendt R F
References (7)
7 references, click to expand
  1. Treatment of respiratory Klebsiella pneumoniae infection in mice with aerosols of kanamycin.
    Antimicrob Agents Chemother. 1975 Nov;8(5):585-90 PMID: 1108778
  2. Influenza virus population dynamics in the respiratory tract of experimentally infected mice.
    Infect Immun. 1976 Feb;13(2):438-47 PMID: 1262060
  3. Lung retention in mice exposed to airborne micro-organisms.
    Nature. 1962 Nov 10;196:598-9 PMID: 13952880
  4. Influenza alone and in sequence with pneumonia due to Streptococcus pneumoniae in the squirrel monkey.
    J Infect Dis. 1975 Dec;132(6):689-93 PMID: 811714
  5. Changing pharyngeal bacterial flora of hospitalized patients. Emergence of gram-negative bacilli.
    N Engl J Med. 1969 Nov 20;281(21):1137-40 PMID: 4899868
  6. Pathogenesis of respiratory Klebsiella pneumoniae infection in rats: bacteriological and histological findings and metabolic alterations.
    Infect Immun. 1977 Feb;15(2):586-93 PMID: 66201
  7. Modified spinning top homogeneous spray apparatus for use in experimental respiratory disease studies.
    Appl Microbiol. 1974 Dec;28(6):929-34 PMID: 4451375
Article Info
Journal
Infection and immunity
Abbr.
Infect Immun
ISSN
0019-9567
DOI
10.1128/iai.20.2.581-583.1978
Published
1978-05-00
Pages
581-3
Language
English
Region
United States
NLM ID
0246127
PMCID
PMC421896
Subset
IM
External Links
PubMed source DOI: 10.1128/iai.20.2.581-583.1978 PMC Full Text View journal details
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