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PMID: 9729721 Published · ppublish English Journal Article Review

BMPs, Smads and metalloproteases: extracellular and intracellular modes of negative regulation.

Current opinion in genetics & development ·Vol. 8 ·No. 4 ·1998-08-00 ·Pages 443-9

Cho KW, Blitz IL

Abstract

Bone morphogenetic (BMPs), members of the TGF-beta superfamily, have critical functions in many biological contexts. Recent findings in Drosophila and vertebrates suggest that BMP signaling can be modulated extracellularly and intracellularly by the availability of BMP inhibitors and Smads, respectively.

MeSH Terms
Animals Bone Morphogenetic Proteins/metabolism Metalloendopeptidases/metabolism Signal Transduction Transforming Growth Factor beta/metabolism
Chemicals
Bone Morphogenetic Proteins Transforming Growth Factor beta Metalloendopeptidases
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Cho K W
Department of Developmental and Cell Biology, University of California, Irvine 92697, USA. [email protected]
Blitz I L
Article Info
Journal
Current opinion in genetics & development
Abbr.
Curr Opin Genet Dev
ISSN
0959-437X
DOI
10.1016/s0959-437x(98)80116-0
Email
[email protected]
Published
1998-08-00
Pages
443-9
Language
English
Region
England
NLM ID
9111375
Subset
IM
External Links
PubMed source DOI: 10.1016/s0959-437x(98)80116-0 View journal details
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