Apoptosis: getting rid of the bodies.

Current biology : CB ·Vol. 8 ·No. 19 ·1998-09-24 ·Pages R693-5

Fadok VA, Henson PM

Abstract

Cells that die by apoptosis need to be removed before lysis to preserve tissue integrity and function. Recent studies have identified components of the uptake machinery used by phagocytes, but much remains to be learnt, particularly about the recognition mechanisms and their coupling to the uptake machinery.

MeSH Terms

ATP-Binding Cassette Transporters/genetics,physiology Animals Apoptosis Apoptosis Regulatory Proteins Caenorhabditis elegans/cytology,genetics,physiology Caenorhabditis elegans Proteins Drosophila melanogaster/cytology,physiology Helminth Proteins/genetics,physiology Humans Insect Proteins/physiology Mammals/physiology Membrane Lipids/physiology Membrane Proteins/genetics,physiology Phagocytosis/genetics,physiology Phosphatidylserines/physiology Phosphoproteins/genetics,physiology Species Specificity Surface Properties

Chemicals

ATP-Binding Cassette Transporters Apoptosis Regulatory Proteins CED-5 protein, C elegans CED-6 protein, C elegans CED-7 protein, C elegans Caenorhabditis elegans Proteins Helminth Proteins Insect Proteins Membrane Lipids Membrane Proteins Phosphatidylserines Phosphoproteins

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Fadok V A

Department of Pediatrics, National Jewish Medical and Research Center, Denver, Colorado 80206, USA.

Henson P M

Article Info

Journal

Current biology : CB

Abbr.

Curr Biol

ISSN

0960-9822

DOI

10.1016/s0960-9822(98)70438-5

Published

1998-09-24

Pages

R693-5

Language

English

Region

England

NLM ID

9107782

Subset

External Links

PubMed source DOI: 10.1016/s0960-9822(98)70438-5 View journal details

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Apoptosis: getting rid of the bodies.

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