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PMID: 9794768 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Haldane's rule in taxa lacking a hemizygous X.

Science (New York, N.Y.) ·Vol. 282 ·No. 5390 ·1998-10-30 ·Pages 952-4

Presgraves DC, Orr HA

Abstract

Haldane's rule states that species hybrids of the XY sex are preferentially sterile or inviable. In all taxa known to obey this rule, the Y is inert and X-linked genes show full expression in XY individuals. Until recently, all theories of Haldane's rule depended on this hemizygosity. A test of Haldane's rule in animals lacking a hemizygous sex-mosquitoes having two functional sex chromosomes in both sexes-reveals that these species show Haldane's rule for sterility but not inviability. A related group having a "normal" hemizygous X obeys Haldane's rule for both sterility and inviability. These results support the faster male and dominance theories of Haldane's rule.

MeSH Terms
Aedes/genetics,physiology Animals Anopheles/genetics,physiology Biological Evolution Crosses, Genetic Female Fertility/genetics Genes, Dominant Genes, Recessive Genetics, Population Genotype Hybridization, Genetic Infertility Male Models, Genetic Sex Characteristics X Chromosome/physiology
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Presgraves D C
Department of Biology, University of Rochester, Rochester, NY 14627, USA.
Orr H A
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
0036-8075
Published
1998-10-30
Pages
952-4
Language
English
Region
United States
NLM ID
0404511
Subset
IM
Corrections
CommentIn
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