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PMID: 9799260 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Different forces drive the evolution of the Acp26Aa and Acp26Ab accessory gland genes in the Drosophila melanogaster species complex.

Genetics ·Vol. 150 ·No. 3 ·1998-11-00 ·Pages 1079-89

Aguadé M

Abstract

The Acp26Aa and Acp26Ab genes that code for male accessory gland proteins are tandemly arranged in the species of the Drosophila melanogaster complex. An approximately 1.6-kb region encompassing both genes has been sequenced in 10, 24, and 18 lines from Spain, Ivory Coast, and Malawi, respectively; the previously studied 10 lines from North Carolina have also been included in the analyses. A total of 110 nucleotide and 4 length polymorphisms were detected. Silent variation for the whole Acp26A region was slightly higher in African than in non-African populations, while for both genes nonsynonymous variation was similar in all populations studied. Based on Fst estimates no major genetic differentiation was detected between East and West Africa, while in general non-African populations were strongly differentiated from both African populations. Comparison of polymorphism and divergence at synonymous and nonsynonymous sites revealed that directional selection acting on amino acid replacement changes has driven the evolution of the Acp26Aa protein in the last 2.5 myr.

MeSH Terms
Amino Acid Sequence Animals Base Sequence Drosophila Proteins Drosophila melanogaster/genetics Evolution, Molecular Genes, Insect Insect Hormones/genetics Intercellular Signaling Peptides and Proteins Male Molecular Sequence Data Peptides/genetics
Chemicals
Acp26Aa protein, Drosophila Acp26Ab protein, Drosophila Acp36DE protein, Drosophila Drosophila Proteins Insect Hormones Intercellular Signaling Peptides and Proteins Peptides SP protein, Drosophila male accessory gland peptide, Drosophila
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Aguadé M
Departament de Genètica, Facultat de Biologia, Universitat de Barcelona, 08071 Barcelona, Spain. [email protected]
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Article Info
Journal
Genetics
Abbr.
Genetics
ISSN
0016-6731
DOI
10.1093/genetics/150.3.1079
Email
[email protected]
Published
1998-11-00
Pages
1079-89
Language
English
Region
United States
NLM ID
0374636
PMCID
PMC1460384
Subset
IM
Databases
GENBANK
AJ231350, AJ231351, AJ231352, AJ231353, AJ231354, AJ231355, AJ231356, AJ231357, AJ231358, AJ231359, AJ231360, AJ231361, AJ231362, AJ231363, AJ231364, AJ231365, AJ231366, AJ231367, AJ231368, AJ231369, AJ231370, AJ231371, AJ231372, AJ231373, AJ231374, AJ231375, AJ231376, AJ231377, AJ231378, AJ231379
External Links
PubMed source DOI: 10.1093/genetics/150.3.1079 PMC Full Text View journal details
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