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PMID: 9809419 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

The ability of probiotic bacteria to bind to human intestinal mucus.

FEMS microbiology letters ·Vol. 167 ·No. 2 ·1998-10-15 ·Pages 185-9

Kirjavainen PV, Ouwehand AC, Isolauri E, Salminen SJ

Abstract

Human mucus was isolated from faecal samples of newborns, two and six month old infants and adults. The adhesion to this mucus by the bacteria mentioned below was assessed in vitro. Depending on the age group: 44-46% of the applied Lactobacillus GG, 23-30% of Bifidobacterium lactis Bb-12, 9-14% of Lactobacillus johnsonii LJ-1, 3-10% of Lactobacillus salivarius LM2-118, Lactobacillus crispatus M247, Lactobacillus paracasei F19 and 2% of L. crispatus Mu5 adhered. All the strains adhered better to the mucus of adults than to that of infants. With some of the strains significant differences between the infant age groups were also observed. In conclusion, the age of the target group may be worthy of consideration when planning a schedule for probiotic or functional food therapy.

MeSH Terms
Adult Aging Bacterial Adhesion Bifidobacterium/metabolism Feces/microbiology Humans Infant Infant, Newborn Intestinal Mucosa/microbiology Lactobacillus/metabolism Middle Aged Probiotics Species Specificity
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Kirjavainen P V
Department of Biochemistry and Food Chemistry, University of Turku, Finland. [email protected]
Ouwehand A C
Isolauri E
Salminen S J
Article Info
Journal
FEMS microbiology letters
Abbr.
FEMS Microbiol Lett
ISSN
0378-1097
Published
1998-10-15
Pages
185-9
Language
English
Region
England
NLM ID
7705721
Subset
IM
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