-
Ubiquitin-dependent protein degradation.
Annu Rev Genet. 1996;30:405-39
PMID: 8982460
-
UBE3A/E6-AP mutations cause Angelman syndrome.
Nat Genet. 1997 Jan;15(1):70-3
PMID: 8988171
-
Reduced ubiquitin-dependent degradation of c-Jun after phosphorylation by MAP kinases.
Science. 1997 Jan 17;275(5298):400-2
PMID: 8994040
-
A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2.
Cell. 1997 Jan 10;88(1):97-107
PMID: 9019411
-
Decreased levels of the cell-cycle inhibitor p27Kip1 protein: prognostic implications in primary breast cancer.
Nat Med. 1997 Feb;3(2):227-30
PMID: 9018244
-
Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas.
Nat Med. 1997 Feb;3(2):231-4
PMID: 9018245
-
Stabilization of beta-catenin by genetic defects in melanoma cell lines.
Science. 1997 Mar 21;275(5307):1790-2
PMID: 9065403
-
p34Cdc28-mediated control of Cln3 cyclin degradation.
Mol Cell Biol. 1995 Feb;15(2):731-41
PMID: 7823941
-
A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase.
Proc Natl Acad Sci U S A. 1995 Mar 28;92(7):2563-7
PMID: 7708685
-
Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin.
Science. 1995 May 5;268(5211):726-31
PMID: 7732382
-
A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B.
Cell. 1995 Apr 21;81(2):279-88
PMID: 7736580
-
The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis.
Mol Biol Cell. 1995 Feb;6(2):185-97
PMID: 7787245
-
Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway.
Genes Dev. 1995 Jul 1;9(13):1586-97
PMID: 7628694
-
Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation.
Cell. 1997 Aug 8;90(3):537-48
PMID: 9267033
-
The ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aos1p/Uba2p heterodimer.
EMBO J. 1997 Sep 15;16(18):5509-19
PMID: 9312010
-
Ubiquitin lys63 is involved in ubiquitination of a yeast plasma membrane protein.
EMBO J. 1997 Oct 1;16(19):5847-54
PMID: 9312043
-
F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex.
Cell. 1997 Oct 17;91(2):209-19
PMID: 9346238
-
A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p.
Cell. 1997 Oct 17;91(2):221-30
PMID: 9346239
-
Relative functions of the alpha and beta subunits of the proteasome activator, PA28.
J Biol Chem. 1997 Oct 31;272(44):27994-8000
PMID: 9346951
-
Characterization of NEDD8, a developmentally down-regulated ubiquitin-like protein.
J Biol Chem. 1997 Nov 7;272(45):28557-62
PMID: 9353319
-
Inhibition of ubiquitin/proteasome-dependent protein degradation by the Gly-Ala repeat domain of the Epstein-Barr virus nuclear antigen 1.
Proc Natl Acad Sci U S A. 1997 Nov 11;94(23):12616-21
PMID: 9356498
-
Regulation of stability and function of the epithelial Na+ channel (ENaC) by ubiquitination.
EMBO J. 1997 Nov 3;16(21):6325-36
PMID: 9351815
-
Inhibition of NF-kappa-B cellular function via specific targeting of the I-kappa-B-ubiquitin ligase.
EMBO J. 1997 Nov 3;16(21):6486-94
PMID: 9351830
-
Regulation of ubiquitin-dependent processes by deubiquitinating enzymes.
FASEB J. 1997 Dec;11(14):1245-56
PMID: 9409543
-
Structure of 20S proteasome from yeast at 2.4 A resolution.
Nature. 1997 Apr 3;386(6624):463-71
PMID: 9087403
-
Ubiquitin C-terminal hydrolase is an immediate-early gene essential for long-term facilitation in Aplysia.
Cell. 1997 Apr 4;89(1):115-26
PMID: 9094720
-
The large subunit of RNA polymerase II is a substrate of the Rsp5 ubiquitin-protein ligase.
Proc Natl Acad Sci U S A. 1997 Apr 15;94(8):3656-61
PMID: 9108033
-
Endoproteolytic cleavage and proteasomal degradation of presenilin 2 in transfected cells.
J Biol Chem. 1997 Apr 25;272(17):11006-10
PMID: 9110991
-
Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway.
Genes Dev. 1997 Apr 15;11(8):957-72
PMID: 9136925
-
Preferential modification of nuclear proteins by a novel ubiquitin-like molecule.
J Biol Chem. 1997 May 30;272(22):14001-4
PMID: 9162015
-
beta-catenin is a target for the ubiquitin-proteasome pathway.
EMBO J. 1997 Jul 1;16(13):3797-804
PMID: 9233789
-
The 'second-codon rule' and autophosphorylation govern the stability and activity of Mos during the meiotic cell cycle in Xenopus oocytes.
EMBO J. 1992 Jul;11(7):2433-46
PMID: 1321032
-
The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53.
Cell. 1993 Nov 5;75(3):495-505
PMID: 8221889
-
Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules.
Cell. 1994 Sep 9;78(5):761-71
PMID: 8087844
-
Ubiquitin-dependent c-Jun degradation in vivo is mediated by the delta domain.
Cell. 1994 Sep 9;78(5):787-98
PMID: 8087846
-
Conjugates of ubiquitin cross-reactive protein distribute in a cytoskeletal pattern.
Mol Cell Biol. 1994 Dec;14(12):8408-19
PMID: 7526157
-
Regulated degradation of the transcription factor Gcn4.
EMBO J. 1994 Dec 15;13(24):6021-30
PMID: 7813440
-
Frameshift mutants of beta amyloid precursor protein and ubiquitin-B in Alzheimer's and Down patients.
Science. 1998 Jan 9;279(5348):242-7
PMID: 9422699
-
The ubiquitin-like proteins SMT3 and SUMO-1 are conjugated by the UBC9 E2 enzyme.
Proc Natl Acad Sci U S A. 1998 Jan 20;95(2):560-4
PMID: 9435231
-
The itchy locus encodes a novel ubiquitin protein ligase that is disrupted in a18H mice.
Nat Genet. 1998 Feb;18(2):143-6
PMID: 9462742
-
The proteasome: paradigm of a self-compartmentalizing protease.
Cell. 1998 Feb 6;92(3):367-80
PMID: 9476896
-
There's the rub: a novel ubiquitin-like modification linked to cell cycle regulation.
Genes Dev. 1998 Apr 1;12(7):901-7
PMID: 9531529
-
A novel protein modification pathway related to the ubiquitin system.
EMBO J. 1998 Apr 15;17(8):2208-14
PMID: 9545234
-
Cytoplasmic tail phosphorylation of the alpha-factor receptor is required for its ubiquitination and internalization.
J Cell Biol. 1998 Apr 20;141(2):349-58
PMID: 9548714
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism.
Nature. 1998 Apr 9;392(6676):605-8
PMID: 9560156
-
Role of a p53 polymorphism in the development of human papillomavirus-associated cancer.
Nature. 1998 May 21;393(6682):229-34
PMID: 9607760
-
Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1.
Nat Genet. 1998 Jun;19(2):148-54
PMID: 9620770
-
Simultaneous binding of PA28 and PA700 activators to 20 S proteasomes.
Biochem J. 1998 Jun 15;332 ( Pt 3):749-54
PMID: 9620878
-
A giant ubiquitin-conjugating enzyme related to IAP apoptosis inhibitors.
J Cell Biol. 1998 Jun 15;141(6):1415-22
PMID: 9628897
-
A function for monoubiquitination in the internalization of a G protein-coupled receptor.
Mol Cell. 1998 Jan;1(2):193-202
PMID: 9659916
-
Degradation signal masking by heterodimerization of MATalpha2 and MATa1 blocks their mutual destruction by the ubiquitin-proteasome pathway.
Cell. 1998 Jul 24;94(2):217-27
PMID: 9695950
-
SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation.
Mol Cell. 1998 Aug;2(2):233-9
PMID: 9734360
-
Degradation of myogenic transcription factor MyoD by the ubiquitin pathway in vivo and in vitro: regulation by specific DNA binding.
Mol Cell Biol. 1998 Oct;18(10):5670-7
PMID: 9742084
-
A protein conjugation system essential for autophagy.
Nature. 1998 Sep 24;395(6700):395-8
PMID: 9759731
-
The ubiquitin system.
Annu Rev Biochem. 1998;67:425-79
PMID: 9759494
-
A novel site for ubiquitination: the N-terminal residue, and not internal lysines of MyoD, is essential for conjugation and degradation of the protein.
EMBO J. 1998 Oct 15;17(20):5964-73
PMID: 9774340
-
Inactivation of the HR6B ubiquitin-conjugating DNA repair enzyme in mice causes male sterility associated with chromatin modification.
Cell. 1996 Sep 6;86(5):799-810
PMID: 8797826
-
Degradation of CFTR by the ubiquitin-proteasome pathway.
Cell. 1995 Oct 6;83(1):121-7
PMID: 7553863
-
Reversible phosphorylation controls the activity of cyclosome-associated cyclin-ubiquitin ligase.
Proc Natl Acad Sci U S A. 1995 Sep 26;92(20):9303-7
PMID: 7568122
-
Signal-induced degradation of I kappa B alpha requires site-specific ubiquitination.
Proc Natl Acad Sci U S A. 1995 Nov 21;92(24):11259-63
PMID: 7479976
-
Control of cell fate by a deubiquitinating enzyme encoded by the fat facets gene.
Science. 1995 Dec 15;270(5243):1828-31
PMID: 8525378
-
A role for the proteasome regulator PA28alpha in antigen presentation.
Nature. 1996 May 9;381(6578):166-8
PMID: 8610016
-
Ubiquitination mediated by the Npi1p/Rsp5p ubiquitin-protein ligase is required for endocytosis of the yeast uracil permease.
J Biol Chem. 1996 May 3;271(18):10946-52
PMID: 8631913
-
The ubiquitin conjugation system is required for ligand-induced endocytosis and degradation of the growth hormone receptor.
EMBO J. 1996 Aug 1;15(15):3806-12
PMID: 8670885
-
A deubiquitinating enzyme interacts with SIR4 and regulates silencing in S. cerevisiae.
Cell. 1996 Aug 23;86(4):667-77
PMID: 8752220
-
Structure and functions of the 20S and 26S proteasomes.
Annu Rev Biochem. 1996;65:801-47
PMID: 8811196
-
Endosome-lysosomes, ubiquitin and neurodegeneration.
Adv Exp Med Biol. 1996;389:261-9
PMID: 8861020
-
The multiubiquitin-chain-binding protein Mcb1 is a component of the 26S proteasome in Saccharomyces cerevisiae and plays a nonessential, substrate-specific role in protein turnover.
Mol Cell Biol. 1996 Nov;16(11):6020-8
PMID: 8887631
-
The N-end rule: functions, mysteries, uses.
Proc Natl Acad Sci U S A. 1996 Oct 29;93(22):12142-9
PMID: 8901547
-
Mechanisms of muscle wasting. The role of the ubiquitin-proteasome pathway.
N Engl J Med. 1996 Dec 19;335(25):1897-905
PMID: 8948566
-
Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction.
Nature. 1996 Dec 5;384(6608):432-8
PMID: 8945469