Knee and/or hip joint destruction in rheumatoid arthritis is associated with HLA-DRB1*0405 in Japanese patients.

Clinical rheumatology ·Vol. 17 ·No. 6 ·1998-00-00 ·Pages 485-8

Wakitani S, Kuwata K, Imoto K, Murata N, Oonishi H, Ochi T

Abstract

To determine the prognostic factors for knee and/or hip joint destruction in rheumatoid arthritis (RA) patients, we typed 379 RA patients for HLA-DRB alleles and analysed the antigen frequencies. The DRB1*0405 antigen frequency in RA patients who underwent total knee replacement and/or total hip replacement was significantly higher than in those who did not have replacements, which meant that DRB1*0405 was associated with knee and/or hip joint destruction. This finding may be of value for predicting knee and/or hip joint destruction in RA.

MeSH Terms

Adolescent Adult Aged Arthritis, Rheumatoid/complications,immunology,surgery Arthroplasty, Replacement, Hip Arthroplasty, Replacement, Knee Female Gene Frequency Genotype HLA-DR Antigens/genetics,immunology HLA-DRB1 Chains Hip Joint/immunology,pathology Humans Japan Knee Joint/immunology,pathology Male Middle Aged Osteoarthritis, Hip/complications,immunology,surgery Osteoarthritis, Knee/complications,immunology,surgery Prognosis

Chemicals

HLA-DR Antigens HLA-DRB1 Chains

Authors & Affiliations

6 authors, click to expand affiliations / ORCID

Wakitani S

Department of Orthopaedic Surgery, Osaka-Minami National Hospital, Kawachinagano, Japan.

Kuwata K

Imoto K

Murata N

Oonishi H

Ochi T

References (12)

12 references, click to expand

A SEVEN-DAY VARIABILITY STUDY OF 499 PATIENTS WITH PERIPHERAL RHEUMATOID ARTHRITIS.
Arthritis Rheum. 1965 Apr;8:302-34 PMID: 14280261
Therapeutic criteria in rheumatoid arthritis.
J Am Med Assoc. 1949 Jun 25;140(8):659-62 PMID: 18150288
Natural course of joint destruction and fluctuation of serum C1q levels in patients with rheumatoid arthritis.
Arthritis Rheum. 1988 Jan;31(1):37-43 PMID: 3257874
The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis.
Arthritis Rheum. 1988 Mar;31(3):315-24 PMID: 3358796
Four common HLA haplotypes and their association with diseases in the Japanese population.
Transplant Proc. 1979 Dec;11(4):1871-3 PMID: 43610
Association between HLA and Japanese patients with rheumatoid arthritis.
Hum Immunol. 1982 Oct;5(2):123-32 PMID: 6815137
Rheumatoid-susceptible alleles of HLA-DRB1 are genetically recessive to non-susceptible alleles in the progression of bone destruction in the wrists and fingers of patients with RA.
Ann Rheum Dis. 1994 Sep;53(9):587-92 PMID: 7979597
Diagnostic and prognostic characteristics of the enzyme linked immunosorbent rheumatoid factor assays in rheumatoid arthritis.
Ann Rheum Dis. 1996 Mar;55(3):157-61 PMID: 8712877
Development of radiographic damage during the first 5-6 yr of rheumatoid arthritis. A prospective follow-up study of a Swedish cohort.
Br J Rheumatol. 1996 Nov;35(11):1106-15 PMID: 8948297
The relationship between HLA-DRB1 alleles and disease subsets of rheumatoid arthritis in Japanese.
Br J Rheumatol. 1997 Jun;36(6):630-6 PMID: 9236671
HLA DRB1* typing and cartilage oligomeric matrix protein (COMP) as predictors of joint destruction in recent-onset rheumatoid arthritis.
Br J Rheumatol. 1997 Aug;36(8):847-9 PMID: 9291852
Elderly-onset rheumatoid arthritis and its association with HLA-DRB1 alleles in Japanese.
Br J Rheumatol. 1998 Jan;37(1):98-101 PMID: 9487258

Article Info

Journal

Clinical rheumatology

Abbr.

Clin Rheumatol

ISSN

0770-3198

DOI

10.1007/BF01451284

Published

1998-00-00

Pages

485-8

Language

English

Region

Germany

NLM ID

8211469

Subset

External Links

PubMed source DOI: 10.1007/BF01451284 View journal details

Analysis Services

Knee and/or hip joint destruction in rheumatoid arthritis is associated with HLA-DRB1*0405 in Japanese patients.

Contact

WeChat Official Account