Home LiteratureArticle Details
PMID: 99430 Published · ppublish English Journal Article

Kasugamycin-resistant mutants of Bacillus subtilis.

Journal of bacteriology ·Vol. 135 ·No. 3 ·1978-09-00 ·Pages 1149-50

Tominaga A, Kobayashi Y

Abstract

Kasugamycin-resistant mutants of Bacillus subtilis were isolated and classified into two groups, one of which had resistance to kasugamycin in in vitro protein synthesis and mapped in the ribosomal region. The other group had no resistance to kasugamycin in in vitro protein synthesis and had weak cross-resistance to gentamicin and kanamycin. Neither group could sporulate in the presence of kasugamycin.

MeSH Terms
Aminoglycosides Anti-Bacterial Agents/pharmacology Bacillus subtilis/drug effects,genetics,physiology Bacterial Proteins/biosynthesis Chromosome Mapping Chromosomes, Bacterial Drug Resistance, Microbial Genes Mutation Spores, Bacterial/physiology
Chemicals
Aminoglycosides Anti-Bacterial Agents Bacterial Proteins
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Tominaga A
Kobayashi Y
References (11)
11 references, click to expand
  1. A third kasugamycin resistance locus, ksgC, affecting ribosomal protein S2 in Escherichia coli K-12.
    J Bacteriol. 1975 May;122(2):796-7 PMID: 1092672
  2. Genetic transduction in Bacillus subtilis.
    Biochem Biophys Res Commun. 1961 Jun 28;5:171-5 PMID: 13774877
  3. A NEW ANTIBIOTIC, KASUGSMYCIN.
    J Antibiot (Tokyo). 1965 Mar;18:101-3 PMID: 14326080
  4. ANTIMICROBIAL ACTIVITY OF KASUGAMYCIN.
    J Antibiot (Tokyo). 1965 Mar;18:104-6 PMID: 14326081
  5. Control of stable RNA synthesis in a temperature-sensitive mutant of elongation factor G of Bacillus subtilis.
    Mol Gen Genet. 1974 May 31;130(3):203-14 PMID: 4210680
  6. Sporulation-specific translational discrimination in Bacillus subtilis.
    J Mol Biol. 1974 Jul 15;86(4):855-63 PMID: 4214933
  7. Functional interdependence among ribosomal elements as revealed by genetic analysis.
    Mol Gen Genet. 1974;133(3):201-7 PMID: 4280504
  8. Mechanism of kasugamycin resistance in Escherichia coli.
    Nat New Biol. 1972 Jan 5;235(53):6-9 PMID: 4336392
  9. Differential inhibition of coliphage MS2 protein synthesis by ribosome-directed antibiotics.
    J Mol Biol. 1972 Sep 14;70(1):41-55 PMID: 4561347
  10. Two genetic loci for resistance to kasugamycin in Escherichia coli.
    J Bacteriol. 1973 Feb;113(2):704-10 PMID: 4570603
  11. Revision of the linkage map of Bacillus subtilis 168: indications for circularity of the chromosome.
    J Bacteriol. 1975 Mar;121(3):823-34 PMID: 803963
Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.135.3.1149-1150.1978
Published
1978-09-00
Pages
1149-50
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC222493
Subset
IM
External Links
PubMed source DOI: 10.1128/jb.135.3.1149-1150.1978 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2