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Dynamic tumor growth patterns in a novel murine model of colorectal cancer

样本量:12 物种:Mus musculus 类型:transcription profiling by array 2014年5月3日

...Apc^Min/+ mice were treated with 4% dextran sodium sulfate to promote colonic tumorigenesis. Tumor growth patterns were...

The effect of TGF-beta in Apc-mutated mouse intestinal organoids

样本量:8 物种:Mus musculus 类型:transcription profiling by array 2014年4月18日

...Apcflox/flox; villin-CreERT mice were treated with Tamoxifen to induce the deletion of Apc. Tamoxifen-treated organoids ...

Gene expression changes in oncogenic Kras-containing, Apc-mutated mouse intes...

样本量:18 物种:Mus musculus 类型:transcription profiling by array 2014年4月18日

...Apc1638N/+ and Apc1638N/+; Kras mice. After the selection procedure, we maintained the cultures with or without TGF-beta...

Apc, Kras, and TGFbeta in intestinal organoids

样本量:26 物种:Mus musculus 类型:transcription profiling by array 2014年4月18日

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

Loss of HDAC11 leads to reduced secretion of MCP-1 and less severe EAE

样本量:2 物种:Mus musculus 类型:transcription profiling by array 2014年3月31日

...APCs) leads to a pro-inflammatory phenotype. Conversely, loss of HDAC11 leads to upregulation of IL-10 and immune tolera...

miR-99a/100~125b tricistrons regulate hematopoietic stem and progenitor cell ...

样本量:10 物种:Homo sapiens 类型:transcription profiling by array 2014年3月28日

...APC/APC2 stabilizes active β-Catenin and enhances Wnt signaling. By switching the balance between Wnt and TGFβ signaling...

Identification of beta-catenin binding regions in SW480 cells

样本量:2 物种:Homo sapiens 类型:ChIP-seq 2014年3月12日

...APC or CTNNB1 (beta-catenin gene) are highly frequent in colon cancer and cause aberrant stabilization of b-catenin, whi...

CytoScanHD array Data for 15 normal, 15 primary colorectal carcinomas and the...

样本量:45 物种:Homo sapiens 类型:comparative genomic hybridization by ... 2014年3月1日

...APC(73%), KRAS (33%), ARID1A and PIK3CA (6.7%) genes between primary colorectal and metastatic liver tumors. TP53 mutati...

Phenotypes of Th lineages generated by the commonly used activation with anti...

样本量:15 物种:Mus musculus 类型:transcription profiling by array 2014年2月13日

...APC). Here, we used TCR-transgenic mice to compare the phenotypes of Th1, Th9 and Th17 lineages when generated by either...

microRNA-135b promotes cancer progression acting as a downstream effector of ...

样本量:24 物种:Mus musculus 类型:transcription profiling by array 2014年1月17日

...APC loss, PTEN/PI3K pathway deregulation and by SRC over-expression and promotes tumor transformation and progression. W...

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