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Expression data from Pax7+ satellite cell derived tumors in vitro and in vivo

样本量:12 物种:Mus musculus 类型:transcription profiling by array 2011年6月1日

...Kras and concomitant loss of p53. Mouse Pax7+ satellite cells were transformed in vitro and in vivo utilizing the Cre-ER...

Discovery of novel recurrent mutations and rearrangements in early T-cell pre...

样本量:577 物种:Homo sapiens 类型:transcription profiling by array 2011年4月20日

...KRAS, FLT3, BRAF, JAK1 and JAK3 in ETP ALL. Moreover, we identified multiple new targets of mutation in including GATA3,...

Pervasive subtypes of pancreatic ductal adenocarcinoma (PDA) and their differ...

样本量:62 物种:Homo sapiens, Mus musculus 类型:transcription profiling by array 2011年4月1日

...KRAS depletion in human PDA cell lines differ substantially between subtypes, and in opposing directions. Integrated gen...

Mutated KRAS induces overexpression of DUSP4, a MAP-kinase phosphatase, and S...

样本量:130 物种:Homo sapiens 类型:transcription profiling by array 2011年3月11日

...KRAS-dependent alterations. The presence of activating KRAS mutations resulted in significant upregulation of 13 genes ...

BRAF Mutation Is Rare in Advanced-Stage Low-Grade Ovarian Serous Carcinomas

样本量:10 物种:Homo sapiens 类型:transcription profiling by array 2011年3月4日

...KRAS. TP53 mutations were not detected in any serous borderline tumors (n = 30) or low-grade serous carcinomas (n = 43) ...

Hierarchical regulation in a KRAS-dependent transcriptional network revealed ...

样本量:64 物种:Rattus norvegicus 类型:transcription profiling by array 2011年3月1日

...KRAS-transformed ovarian surface epithelium cell lines. The reconstructed model shows that the investigated components a...

Rhabdomyosarcoma can be initiated in activated Pax7+ Muscle Progenitor Cells

样本量:28 物种:Mus musculus 类型:transcription profiling by array 2011年1月30日

...Kras and p53 using both in vivo and in vitro approaches to identify a cell of origin for rhabdomyosarcoma. Contains rhab...

Promotion of Lung Tumorigenesis By Beta-catenin

样本量:6 物种:Mus musculus 类型:transcription profiling by array 2011年1月28日

...KrasG12D alone. We show that activation of Wnt/β- catenin signaling significantly alters the KrasG12D tumor phenotype re...

Suppression of Lung Adenocarcinoma Progression by Nkx2-1

样本量:29 物种:Mus musculus 类型:transcription profiling by array 2011年1月27日

...Kras and deletion of p53 in the lung epithelial cells of KrasLSL-G12D/+;p53flox/flox mice initiates lung adenocarcinoma...

Integrated mutation, copy number and expression profiling in resectable non-s...

样本量:170 物种:Homo sapiens 类型:transcription profiling by array 2010年11月27日

...KRAS mutation; TP53 mutation, metastatic potential and disease recurrence and survival. Amplification of 3q was associat...

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