...KRAS- or BRAF-mediated signal transduction is a prerequisite for the expression of neoplastic phenotypes; however, the m...
...Kras mutants and 3 controls, on the Illumina Mouse-6 Beadchip array.
...Kras and 9 Kras/Lkb1 primary tumors as well as 17 Kras/Lkb1 metastases (lymph node and distant sites)
...KRAS, BRAF and TP53 are present but generally rare. However, integrative analysis of mutations with copy number alterati...
...KRAS, HRAS, NRAS, TP53, CDKN2A, and TSC1, in 103 of these cases. Hierarchical cluster analysis identified two intrinsic ...
...KRAS mutation does not enhance melanocyte proliferation and is only weakly tumorigenic on its own. While both NRAS and K...
...kras, Asp, Val) were compared to non-transfected cell line. For each of the four comparison 4 chip experiments were perf...
A genome-wide survey of transcriptional targets responding to chronic KRAS/MAPK (mitogen-activated protein kinase) pathw...
...KRAS, TP53 and loss of 18q were analyzed. Genes whose expression correlated with the underlying copy number pattern were...
K-ras is one of the most frequently mutated human oncogenes. However, activation of K-ras can lead to either senescence...
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