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KRAS-induced transcription analysis in immortalized pancreatic cells

样本量:16 物种:Homo sapiens 类型:transcription profiling by array 2016年1月19日

...KRAS (>90% PDAC tumors) and its early role in pancreatic neoplasia, we sought to engineer HPDE cells containing KRASG12D...

Epigenomic profiling of Non-small-cell Lung Cancer (NSCLC) cells with or with...

样本量:31 物种:Homo sapiens, Mus musculus 类型:ChIP-seq, RNA-seq of coding RNA 2016年1月15日

...Kras-driven non-small-cell lung cancer (NSCLC) progression. Modulation of PRC2 by either Ezh2 overexpression or Eed dele...

High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Can...

样本量:5 物种:Homo sapiens 类型:RNA-seq of coding RNA 2015年11月25日

...KRAS backgrounds. Thus, rigorous identification of human cell line fitness genes using a high-complexity CRISPR-Cas9 lib...

BCL9/9L-β-catenin Signaling is Associated With Poor Outcome in Colorectal Cancer

样本量:25 物种:Mus musculus 类型:RNA-seq of coding RNA 2015年11月8日

...Kras tumors and healthy colocyte extracts.

Oncogenic deregulation of EZH2 as an opportunity for targeted therapy in lung...

样本量:7 物种:Mus musculus 类型:RNA-seq of coding RNA 2015年11月1日

...KRAS- and EGFR-mutant mouse lung cancers, but shared with human lung adenocarcinomas exhibiting high EZH2 expression. To...

Oncogenic deregulation of EZH2 as an opportunity for targeted therapy in lung...

样本量:12 物种:Mus musculus 类型:ChIP-seq 2015年11月1日

...KRAS- and EGFR-mutant mouse lung cancers, but shared with human lung adenocarcinomas exhibiting high EZH2 expression. To...

Global mRNA expression profiling of murine primary PDAC cells following JQ1 o...

样本量:4 物种:Mus musculus 类型:transcription profiling by array 2015年9月20日

...Kras+/LSL-G12D;p53lox/lox (Kras;p53) mice were treated either with JQ1 (100 nM) or SAHA (2000 nM) or vehicle 10% (2-Hydr...

Simultaneous amplification and mutation of KRAS: a therapeutic target in a ra...

样本量:2 物种:Homo sapiens 类型:comparative genomic hybridization by ... 2015年9月19日

...KRAS. sample was analysed by arrayCGH method using Agilent recommendations. Sample was labeled in Cy5 and co-hybridized ...

Expression data comparing KRas(G12D/+);CreT, R26(H1047R/+);KRas(G12D/+);CreT,...

样本量:15 物种:Mus musculus 类型:transcription profiling by array 2015年9月16日

...KRas(G12D/+);CreT and R26(H1047R/+);KRas(G12D/+);CreT tumors Total RNA was extracted from tumors developed by Qiagen RNA...

Analysis of therapeutic miRNA against KRAS mutant colorectal cancer

样本量:4 物种:Homo sapiens 类型:transcription profiling by array 2015年9月1日

...KRAS mutant cancers, we transfected exogenous KRASG12V into HEK293 and MRC5 cells with wild type KRAS genes, and we comp...

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