During activation, T cells integrate multiple signals from APCs and cytokine milieu. The blockade of these signals can h...
...Apc loss. However c-Myc deletion, which rescues the phenotypes of Apc loss in the intestine, had no effect on the phenot...
...ApcFlox) to investigate the consequences of perturbation of Wnt signalling following inactivation of Apc in vivo within ...
...APC deletion; K = KRAS G12V knock in; S = Smad4 deletion; T = TP53 deletion; P = PIK3CA E545K knock in. 2) Genome-engine...
...aPC, CLP+Vehicle, CLP+aPC; n=3/group) and pooled.
...APC tumor suppressor in the intestinal epithelium. We demonstrate that this phenotype is independent of both the activat...
...APC genomic fingerprints are significantly influenced by the tissue of origin as well as by individual APC subsets. None...
...Apc Min/+ and Apc Min/+:Rad21+/- double mutant mouse; Mapping of Rad21 genomic binding sites in normal intestinal crypts...
...APC, including the IFN response, inflammation, DC maturation, T cell activation, antigen processing, cell motility and h...
...APC, including the IFN response, inflammation, DC maturation, T cell activation, antigen processing, cell motility and h...
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