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KRAS-Dependent Sorting of miRNAs and other small RNAs to secreted vesicles

样本量:18 物种:Homo sapiens 类型:RNA-seq of non coding RNA 2015年8月28日

...KRAS-derived exosomes. Ceramide inhibition resulted in accumulation of miR-100 in mutant KRAS cells, suggesting KRAS-de...

RelA in pancreatic cancer

样本量:6 物种:Mus musculus 类型:transcription profiling by array 2015年8月15日

...Kras expressing mouse pancreata in comparison to pancreata with concomitant RelA deletion

Targeting β-catenin overcomes resistance to MEK inhibitor in PIK3CA mutant co...

样本量:4 物种:Homo sapiens 类型:proteomic profiling by array 2015年8月13日

...KRAS mutation, offered resistance to MEK inhibitor through activation of PI3K-AKT signaling. We identified a gene that c...

Assessment of MEK-ERK pathway targeting by BRAF, NRAS and KRAS gene mutations...

样本量:4 物种:Homo sapiens 类型:transcription profiling by array 2015年7月1日

...KRAS genes. We evaluated the relationship of identified variants with other clinical and biological features and determi...

Assessment of MEK-ERK pathway targeting by BRAF, NRAS and KRAS gene mutations...

样本量:142 物种:Homo sapiens 类型:transcription profiling by array 2015年7月1日

...KRAS genes. We evaluated the relationship of identified variants with other clinical and biological features and determi...

Assessment of MEK-ERK pathway targeting by BRAF, NRAS and KRAS gene mutations...

样本量:146 物种:Homo sapiens 类型:transcription profiling by array 2015年7月1日

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

Oncogene-dependent regulation of tumor cells via stromal reciprocal signallin...

样本量:8 物种:Mus musculus 类型:RNA-seq of coding RNA 2015年6月27日

...KRASG12D), a trans-cellular signal (SHH), and stromal cells drive a reciprocal response in tumor cells. KRASG12D-depende...

Expression profiling of 40 NSCLC cell lines

样本量:40 物种:Homo sapiens 类型:transcription profiling by array 2015年6月22日

...KRAS, and STK11, however, the major inactivation mechanism of p16 varied. p16 methylation was linked to KRAS mutation bu...

The RALA pathway can maintain the proliferation of KRAS- and BRAF-mutated can...

样本量:15 物种:Homo sapiens 类型:transcription profiling by array 2015年6月20日

...KRAS (codon 12 or 13) or a mutated BRAF can have significant functions in colorectal cancer carcinogenesis. RALA was sil...

Apc restoration promotes cellular differentiation and reestablishes crypt hom...

样本量:20 物种:Mus musculus 类型:RNA-seq of coding RNA 2015年6月18日

...Kras and p53 mutations, can progress to invasive carcinoma. In established tumors, Apc restoration drives rapid and wide...

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