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ACKR2 aids the regulation of bone marrow eosinophils to promote monocyte diff...

Wilson(GJ),Foley(LK),Pocalun(Z),Pitmon(E),... Nat Commun 2026-07-22

...ACKR2. In the absence of ACKR2, there are decreased numbers of eosinophils in the bone marrow. As a result, eosinophil a...

α 1A-Adrenergic receptor (ADRA1A) signaling signatures as prognostic biomarke...

Beltrán-Navarro(YM),Vázquez-Prado(J),Reyes... In Silico Pharmacol None

...ACKR2, DRD1, ADRA1B, GPR17, S1PR1, and GPR182, and RTKs like KDR and TEK similarly integrated transcriptional signatures...

CCL14, identified by multi-omics approach, serves as a novel indicator of dis...

Bai(W),Hua(L),Wang(X),Guo(M),Chen(L),Liu(B... Orphanet J Rare Dis 2026-01-20

...ACKR2, CCR3 and CCR1. Clinically, plasma CCL14 levels were significantly elevated in LAM patients versus controls (p = 0...

Ginsenoside Rg1 Ameliorates LPS-Induced Sepsis-Associated Lung Injury in Mice...

Wang(H),Hu(L),Zhang(CP),Qi(WJ),Song(YG) Kaohsiung J Med Sci 2026-05-07

...ACKR2). Ginsenoside Rg1 can attenuate septic ALI by stimulating the VEGFC/D-VEGFR3 axis to promote functional lymphangio...

Identification and expression analysis of an atypical chemokine receptor-2 (A...

Qi(Zhitao),Jiang(Yousheng),Holland(Jason W... Fish Shellfish Immunol 2016-01-28

...ACKR2 molecules is supported by their conserved structure, and by phylogenetic tree and synteny analysis. Trout ACKR2 is...

Renal Protection by Genetic Deletion of the Atypical Chemokine Receptor ACKR2...

Zheng(Shirong),Coventry(Susan),Cai(Lu),Pow... J Diabetes Res 2016-10-24

...ACKR2(-/-) mice to test whether ACKR2 elimination alters progression of diabetic kidney disease. Elimination of ACKR2 gr...

The atypical chemokine receptor ACKR2 suppresses Th17 responses to protein au...

Hansell(Chris A H),MacLellan(Lindsay M),Ol... Immunol Cell Biol 2015-12-14

...ACKR2 is also universally expressed by innate-like B cells, suppressing their responsiveness to the non-ACKR2 ligand CXC...

Atypical chemokine receptor ACKR2 mediates chemokine scavenging by primary hu...

Teoh(Pek Joo),Menzies(Fiona M),Hansell(Chr... J Immunol 2015-02-24

...ACKR2), previously known as D6. ACKR2 binds many inflammatory CC chemokines but cannot stimulate cell migration or activ...

The N-terminal region of the atypical chemokine receptor ACKR2 is a key deter...

Hewit(Kay D),Fraser(Alasdair),Nibbs(Robert... J Biol Chem 2014-08-02

...ACKR2, which regulates ligand binding. Here we demonstrate that a conserved tyrosine motif at the N terminus of ACKR2 is...

Characterization of conventional and atypical receptors for the chemokine CCL...

Ford(Laura B),Cerovic(Vuk),Milling(Simon W... J Immunol 2014-08-18

...ACKR2. We confirm the unique, overlapping, ligand specificities of CCR2 and ACKR2 and, unexpectedly, find that cell cont...

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