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Isolation and characterization of cancer stem cells from cervical cancer HeLa...

Zhang(Song-Ling),Wang(Yi-Shu),Zhou(Tong),Y... Cytotechnology 2016-01-21

...Bcrp1-positive cells was greater than that of the Bcrp1-negative cells (P < 0.05). In the invasion assay, the Bcrp1-posi...

Intracellular accumulation of boceprevir according to plasma concentrations a...

Cusato(Jessica),Allegra(Sarah),De Nicolò(A... Int J Antimicrob Agents 2016-02-02

...BCRP1 and SLC28A2 predicted the S isomer PBMC/plasma concentration ratio. No similar data regarding BOC pharmacogenetics...

Synthesis and Preclinical Evaluation of Three Novel Fluorine-18 Labeled Radio...

Savolainen(Heli),Cantore(Mariangela),Colab... Mol Pharm 2016-03-31

...Bcrp1((-/-)) and wild-type mice were used to assess the substrate potential in vivo. Comparison was made to (R)-[(11)C]v...

ABCG2/BCRP interaction with the sea grass Thalassia testudinum.

Miguel(Verónica),Otero(Jon A),Barrera(Borj... Drug Metab Pers Ther 2016-08-22

...Bcrp1 were performed.,T. testudinum extract could be included as MDR modulator, as interaction with ABCG2/BCRP has been ...

Efficacy of PARP Inhibitor Rucaparib in Orthotopic Glioblastoma Xenografts Is...

Parrish(Karen E),Cen(Ling),Murray(James),C... Mol Cancer Ther 2016-09-20

...BCRP1 or human MDR1, cell accumulation studies demonstrated that rucaparib is transported by both transporters. Consiste...

The antiepileptic drug lamotrigine is a substrate of mouse and human breast c...

Römermann(Kerstin),Helmer(Renate),Löscher(... Neuropharmacology 2016-01-01

...Bcrp1 or human BCRP to evaluate whether AEDs are substrates of this major efflux transporter. Six of 7 AEDs examined, na...

Systemic and CNS activity of the RET inhibitor vandetanib combined with the m...

Subbiah(Vivek),Berry(Jenny),Roxas(Michael)... Lung Cancer 2016-03-03

...Bcrp1/Abcg2) but is not transported by P-glycoprotein (P-gp), limiting its blood-brain barrier penetration. A co-adminis...

Oncolytic adenovirus‑mediated mda‑7/IL‑24 expression suppresses osteosarcoma ...

Liu(Zongming),Xu(Libo),Yuan(Hongping),Zhan... Mol Med Rep 2016-07-21

...BCRP1, as well as minimized autophagy. Furthermore, restoring Pgp and BCRP1 expression as well as autophagy, was able to...

Consecutive salinomycin treatment reduces doxorubicin resistance of breast tu...

Hermawan(Adam),Wagner(Ernst),Roidl(Andreas... Oncol Rep 2016-10-27

...BCRP1. We found that repeated treatment with salinomycin generated resistance against this drug in all cell lines and in...

Curcumin Affects Phase II Disposition of Resveratrol Through Inhibiting Efflu...

Ge(Shufan),Yin(Taijun),Xu(Beibei),Gao(Song... Pharm Res 2016-10-24

...Bcrp1 (-/-) mice. Human UGT1A9-overexpressing HeLa cells and human MRP2-overexpressing MDCK II-UGT1A1 cells were used as...

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