Prasitsumrit(V),Chen(VL) Curr Opin Gastroenterol 2026-05-01

...GCKR are strongly associated with steatosis but much more weakly associated with advanced liver disease. The cirrhosis-a...

Santoleri(D),Traynor(S),Calhoun(R),Gavin(M... bioRxiv 2026-06-11

...GCKR , the gene encoding GKRP, strongly associate with fatty liver disease, hypertriglyceridemia, and hypercholesterolem...

Jiménez-Ortega(RF),López-Pérez(TV),Aparici... Nutr Metab Cardiovasc Dis 2026-08-00

Previous studies have reported that genetic variants in the GCKR, FADS1, BCO1, and FGF21 genes are associated with lipid...

Ding(K),Xiang(L),Jiang(W),Lei(M),Gao(Y) J Mol Endocrinol 2026-04-01

...GCKR (FDR < 0.05), which gsMap showed to be highly expressed in hepatocytes and liver tissue. The present study revealed...

Musafer(KNJ),Ali(A),Din(TADAAT),Arafat(HM)... Diabetol Metab Syndr 2026-04-07

...GCKR rs780094 (OR = 3.99, p = 0.001), and TCF7L2 rs12255372 (OR = 2.06, p = 0.0001); additional signals were observed fo...

Fteah(AM),Aly(DM),Elrefaiy(MA),Rahim(AA) BMC Gastroenterol 2026-04-13

...GCKR) and fibroblast growth factor 21 (FGF21), together with circulating FGF21 concentrations, on susceptibility to MASL...

Jeyaraj(FT),Vennam(SS),Nelson(K),Watts(K),... Food Funct 2026-04-14

...GCKR and triglycerides and rs58542926 in TMS6F2. This pilot study shows a potential role of genetics in liver fat change...

Zhang(J),Song(K),Han(W),Wang(Z),Cao(G) Metabolites 2026-07-30

...GCKR (PP.H4 = 1.000). Cross-cohort human plasma profiling across 2058 patients confirmed the systemic detectability of 2...

Crespo(J),Alonso-Peña(M),Jiménez-González(... Pharmaceuticals (Basel) 2026-07-24

...GCKR, HSD17B13, MTARC1, GPAM, and CIDEB-have substantially expanded the mechanistic understanding of disease heterogenei...

Guariglia(M),Caviglia(GP),Gaia(S),Rosso(C)... Front Oncol None

...GCKR rs780094, and HSD17B13 rs72613567 variants were genotyped. An independent cohort of viral-related HCC (n = 384) was...