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Hematopoietic Cell Kinase Promotes Cerebral Ischemic Injury and Mitochondrial D…

Lv(Y),Ba(M),Liang(Z),Xiang(J),Sun(Q) Mol Neurobiol 2026-03-30

...HCK expression was significantly upregulated following cerebral ischemia. HCK knockdown markedly attenuated cerebral inj...

Systematic prioritization of potential therapeutic targets for glomerulonephrit…

Li(G),Jianhan(F),Gu(J),Wang(Y),Liu(J),Yang(D… PLoS Comput Biol 2026-04-00

...HCK as a risk factor for membranous nephropathy, whereas CD302 and CDKN1B showed protective effects. Transcriptomic-wide...

Regulation of Starch-Lauric Acid Complex Properties by Amylose Molecular Weight…

Zhang(M),Li(Z),Gu(Z),Ban(X),Hong(Y),Cheng(L)… J Agric Food Chem 2026-04-15

...HCK) and low-MW (CGK) amylose with lauric acid by using an in vitro digestion-fermentation model. A distinct paradox eme...

Hematopoietic cell kinase regulates microglial/macrophage activation to drive n…

Li(L),Lu(T),Gao(W),Li(F),Guo(X),Guan(S),Ghey… Cell Commun Signal 2026-04-09

...HCK), a central node within this hub gene network. Pharmacological inhibition of HCK kinase activity with A-419259 was f...

Sustainable Hydrochars from Winery Waste for the Efficient Removal of Organopho…

Petrović(J),Koprivica(M),Milenković(M),Erceg… Int J Mol Sci 2026-03-25

...HCK and pseudo-second-order adsorption for AZM on HCK and all pollutants on PHC. Thermodynamic analysis confirmed that a...

NIPAL1 Drives a Metabolic-Epigenetic Feedback Loop to Promote Lactate-Mediated …

Chen(RX),Ma(XD),Xu(SD),Mo(AT),Deng(MH),Wu(JH… Adv Sci (Weinh) 2026-05-00

...HCK to phosphorylate LDHA at Y10, enhancing glycolysis and lactate production. Lactate accumulation promotes p300-mediat...

Study on the mechanism of 18β-glycyrrhetinic acid inhibiting the proliferation …

Jia(S),Zhang(L),Li(Y),Xu(D),Yang(Y),Zhou(Z),… Front Oncol None

...HCK, CASP1 and IDO1, with its mechanism linked to the autophagy pathway via functional enrichment analysis; whole transc...

The dual-specificity phosphatase JSP1 regulates neutrophil adhesion via integri…

Li(L),Tonks(NK) J Biol Chem 2026-05-00

...HCK phosphorylation in JSP1-knockout neutrophils is consistent with a mechanism involving impaired integrin-SRC signalin...

Leveraging ADMET Profiling, Network Pharmacology, and Molecular Docking to Eval…

Ugbaja(SC),Nkabinde(SA),Nkabinde(M),Gqaleni(… Biomedicines 2026-04-30

...HCK (-10.5 vs. -7.9 kcal/mol), diosgenin toward EGFR (-9.4 vs. -8.4 kcal/mol), rutin toward SRC (-10.5 vs. -7.8 kcal/mol...

Exogenous Quercetin Enhances Salt Tolerance in Apocynum venetum Seedlings: Insi…

Zhao(X),Buttar(ZA),Zhao(B),Jiang(L) Physiol Plant None

...HCK (control), HCKN (salt stress), Q3 (quercetin), and Q3 + N (quercetin + salt stress). These findings demonstrated tha...

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