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Machado(AL),Pinto(A),Carvalho(J),Fernandes... Cell Oncol (Dordr) 2026-02-12

...KRAS mutations had higher KRAS signaling scores than KRAS-mutant tumors with low uptake, highlighting a central role of ...

Yim(H),Song(X),Zhong(Y),Hu(J),Xiong(Y),Jin(J) Eur J Med Chem 2026-04-05

...KRAS-G12D degraders that recruit one of four E3 ligases (CRBN, VHL, DCAF1, or KLHDC2) using a common KRAS-G12D binder de...

van Tienen(LM),Bayoumi(S),Muneeruddin(K),L... Cell Chem Biol 2026-02-19

...KRAS(G12D) variants, purifying KRAS Cys-variants and screening them against 47 covalent compounds, quantifying accessibi...

Liao(L),Li(Y),Liu(J),Li(Y),Ma(J),Qi(Y),Ma(... Photodiagnosis Photodyn The... 2026-04-00

...KRAS, a common oncogenic mutant gene, has a mutation frequency of up to 40% in colorectal cancer and significantly impac...

Bartl(T),Cacsire Castillo-Tong(D) Int J Gynecol Cancer 2026-04-00

...KRAS mutations [50%-65%] and near-universal MAPK hyperactivation) constitutes a defining feature of mucinous ovarian can...

Carion(M),Cuesta(R),Kowalczyk(D),Smets(W),... Biochemistry 2026-03-03

...KRAS and NRAS, they remain effective against HRAS-driven tumors and other pathologies, such as Hutchinson-Gilford proger...

Lee(JK),Yoon(JY),Lee(JY),Lee(SH) Int J Mol Sci 2026-01-23

...KRAS-wild-type), and HCT-8 and LoVo (KRAS-mutant), co-immunoprecipitation showed that PrPC forms complexes with the 37/6...

Coronel-Hernández(J),Rodríguez-Izquierdo(F... Int J Mol Sci 2026-01-30

...KRAS pathways commonly linked to angiogenesis, migration, and invasion. This preliminary report highlights a 25-gene der...

Psaras(AM),McKay(SJ),Vasquez Vilela(J),Osp... Int J Mol Sci 2026-02-05

...KRAS inhibitor BI2865-to investigate whether KRAS modulation enhances chemotherapeutic efficacy in ovarian cancer models...

Gutmans(J),Friedlaender(A),Mechahougui(H) Int J Mol Sci 2026-02-06

...KRAS mutations are enriched in pancreatobiliary tumors. We recommend early application of a rapid-core panel (KRAS/BRAF,...